颅内压与青光眼。
Intracranial pressure and glaucoma.
机构信息
Vance Thompson Vision, 1310 W 22nd Street, Sioux Falls, South Dakota, USA.
出版信息
Curr Opin Ophthalmol. 2010 Mar;21(2):106-11. doi: 10.1097/ICU.0b013e32833651d8.
PURPOSE OF REVIEW
Glaucoma remains a disease with an unclear basic pathophysiology. The optic nerve travels through two pressurized regions: the intraocular space and the intracranial space. Some authors have suggested that the relationship between intraocular pressure and intracranial pressure may play a fundamental role in the development of glaucoma.
RECENT FINDINGS
Recent studies have shown that intracranial pressure is lower in patients with glaucoma and normal-tension glaucoma. Conversely, intracranial pressure appears to be elevated in patients with ocular hypertension. Early mathematical modeling studies have suggested that the counterbalance provided by intracranial pressure would be an important factor in the development of glaucoma.
SUMMARY
The relationship between intraocular pressure and intracranial pressure may play an important role in the development of glaucoma.
目的综述
青光眼的基础病理生理学仍不明确。视神经穿行于两个受压迫区域：眼内空间和颅内空间。一些作者认为眼内压与颅内压之间的关系可能在青光眼的发生发展中起重要作用。
最近的发现
最近的研究表明，青光眼和正常眼压性青光眼中颅内压较低。相反，高眼压症患者的颅内压似乎升高。早期的数学模型研究表明，颅内压的平衡作用可能是青光眼发生发展的一个重要因素。
总结
眼内压与颅内压之间的关系可能在青光眼的发生发展中起重要作用。
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