农药喷雾器操作人员血浆丁酰胆碱酯酶活性及血液学参数监测
Monitoring of plasma butyrylcholinesterase activity and hematological parameters in pesticide sprayers.
作者信息
Rastogi S K, Singh Vipul K, Kesavachandran C, Siddiqui M K J, Mathur N, Bharti R S
出版信息
Indian J Occup Environ Med. 2008 Apr;12(1):29-32. doi: 10.4103/0019-5278.40813.
To evaluate the health impact of spraying organophosphorus insecticides (OPs), 34 male sprayers in the mango belt of Malihabad, a small town located 27 km from Lucknow in North India was selected. Plasma butyryl cholinesterase (PBChE) and complete blood count were assessed among sprayers after spraying pesticides and the findings obtained were compared with those determined in a reference group (n = 18). The most common symptoms observed were burning sensation in the eyes (8.82%), itching/skin irritation (23.52%) and chest symptoms (32.35%) in the exposed workers. Plasma butyrylcholinesterase (PBChE) was significantly decreased in workers. The results indicated significant decrease in the mean value of hemoglobin, hematocrit and platelets count; however, significantly higher count of leukocytes was also observed in the exposed group (sprayers) compared to that observed in the control group (P < 0.05). Monitoring of PBChE in pesticide sprayers could be useful to predict and prevent health hazards of OPs.
为评估喷洒有机磷杀虫剂（OPs）对健康的影响，我们选取了位于印度北部、距离勒克瑙27公里的小镇马利哈巴德芒果种植带的34名男性喷洒工。在喷洒农药后，对这些喷洒工的血浆丁酰胆碱酯酶（PBChE）和全血细胞计数进行了评估，并将所得结果与对照组（n = 18）的结果进行比较。在暴露工人中观察到的最常见症状是眼睛烧灼感（8.82%）、瘙痒/皮肤刺激（23.52%）和胸部症状（32.35%）。工人的血浆丁酰胆碱酯酶（PBChE）显著降低。结果表明，血红蛋白、血细胞比容和血小板计数的平均值显著下降；然而，与对照组相比，暴露组（喷洒工）的白细胞计数也显著更高（P < 0.05）。监测农药喷洒工的PBChE可能有助于预测和预防OPs的健康危害。
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