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一例晚期妇科盆腔肿瘤病例,展示了 HPV 分析的诊断效用。

A case of advanced gynecologic pelvic tumors showing the diagnostic utility of HPV analysis.

机构信息

Department of Obstetrics and Gynecology, The Catholic University of Korea College of Medicine, Seoul, Korea.

出版信息

J Gynecol Oncol. 2009 Dec;20(4):251-3. doi: 10.3802/jgo.2009.20.4.251. Epub 2009 Dec 28.

Abstract

Gynecologic malignancies may have similar histological characteristics. This may lead to difficulties in determining the origin of the cancer and to distinguish a synchronous neoplasm from a metastatic cancer in advanced cases. Recently, we treated a 59-year-old patient with adenocarcinoma of the uterine cervix, endometrium, fallopian tubes, and ovaries. It was difficult to determine whether the cancer was a single origin metastatic cancer or a synchronous neoplasm. The patient was finally diagnosed with metastatic cancer that originated from the uterine cervix by human papillomavirus (HPV) test. Here we report the case and briefly review of the medical literature.

摘要

妇科恶性肿瘤可能具有相似的组织学特征。这可能导致在确定癌症的起源方面出现困难,并在晚期病例中区分同步肿瘤与转移性癌症。最近,我们治疗了一名 59 岁的宫颈癌、子宫内膜癌、输卵管癌和卵巢腺癌患者。难以确定癌症是单一起源的转移性癌症还是同步肿瘤。通过人乳头瘤病毒 (HPV) 检测,患者最终被诊断为源自宫颈癌的转移性癌症。在此,我们报告该病例并简要复习文献。

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引用本文的文献

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Three cases of women with HPV-related squamous cell carcinoma of unknown primary in the pelvis and retroperitoneum: A case series.
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本文引用的文献

4
Utility of HPV analysis for evaluation of possible metastatic disease in women with cervical cancer.
Int J Gynecol Pathol. 2004 Jan;23(1):7-12. doi: 10.1097/01.pgp.0000101084.35393.03.
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