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1
Interrupted catalysis: the EF4 (LepA) effect on back-translocation.
J Mol Biol. 2010 Mar 5;396(4):1043-52. doi: 10.1016/j.jmb.2009.12.043. Epub 2010 Jan 4.
2
A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.
Nat Struct Mol Biol. 2008 Sep;15(9):910-5. doi: 10.1038/nsmb.1469.
3
EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome.
Nat Struct Mol Biol. 2016 Feb;23(2):125-31. doi: 10.1038/nsmb.3160. Epub 2016 Jan 25.
4
The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis.
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16223-8. doi: 10.1073/pnas.1103820108. Epub 2011 Sep 19.
7
Dynamics of forward and backward translocation of mRNA in the ribosome.
PLoS One. 2013 Aug 9;8(8):e70789. doi: 10.1371/journal.pone.0070789. eCollection 2013.
9
The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome.
Cell. 2006 Nov 17;127(4):721-33. doi: 10.1016/j.cell.2006.09.037.

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1
Lacticaseibacillus paracasei AD22 Stress Response in Brined White Cheese Matrix: In Vitro Probiotic Profiles and Molecular Characterization.
Probiotics Antimicrob Proteins. 2025 Jun;17(3):1725-1738. doi: 10.1007/s12602-024-10216-4. Epub 2024 Feb 29.
2
Functions and Regulation of Translation Elongation Factors.
Front Mol Biosci. 2022 Jan 19;8:816398. doi: 10.3389/fmolb.2021.816398. eCollection 2021.
3
Optimization of a fluorescent-mRNA based real-time assay for precise kinetic measurements of ribosomal translocation.
RNA Biol. 2021 Dec;18(12):2363-2375. doi: 10.1080/15476286.2021.1913312. Epub 2021 May 3.
4
Omnipresent Maxwell's demons orchestrate information management in living cells.
Microb Biotechnol. 2019 Mar;12(2):210-242. doi: 10.1111/1751-7915.13378.
5
Translation Elongation Factor 4 (LepA) Contributes to Tetracycline Susceptibility by Stalling Elongating Ribosomes.
Antimicrob Agents Chemother. 2018 Jul 27;62(8). doi: 10.1128/AAC.02356-17. Print 2018 Aug.
6
Roles of elusive translational GTPases come to light and inform on the process of ribosome biogenesis in bacteria.
Mol Microbiol. 2018 Feb;107(4):445-454. doi: 10.1111/mmi.13895. Epub 2017 Dec 29.
7
Taking a Step Back from Back-Translocation: an Integrative View of LepA/EF4's Cellular Function.
Mol Cell Biol. 2017 May 31;37(12). doi: 10.1128/MCB.00653-16. Print 2017 Jun 15.
8
Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome.
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):980-985. doi: 10.1073/pnas.1613665114. Epub 2017 Jan 17.
9
Similarity and diversity of translational GTPase factors EF-G, EF4, and BipA: From structure to function.
RNA Biol. 2016 Dec;13(12):1258-1273. doi: 10.1080/15476286.2016.1201627. Epub 2016 Jun 20.
10
Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome.
J Biol Chem. 2016 Jun 17;291(25):12943-50. doi: 10.1074/jbc.M116.725945. Epub 2016 May 2.

本文引用的文献

2
Transient ribosomal attenuation coordinates protein synthesis and co-translational folding.
Nat Struct Mol Biol. 2009 Mar;16(3):274-80. doi: 10.1038/nsmb.1554. Epub 2009 Feb 8.
3
A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.
Nat Struct Mol Biol. 2008 Sep;15(9):910-5. doi: 10.1038/nsmb.1469.
4
New features of the ribosome and ribosomal inhibitors: non-enzymatic recycling, misreading and back-translocation.
J Mol Biol. 2008 Jun 27;380(1):193-205. doi: 10.1016/j.jmb.2008.04.060. Epub 2008 May 2.
5
The structure of LepA, the ribosomal back translocase.
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4673-8. doi: 10.1073/pnas.0801308105. Epub 2008 Mar 24.
6
Following molecular transitions with single residue spatial and millisecond time resolution.
Methods Cell Biol. 2008;84:589-615. doi: 10.1016/S0091-679X(07)84019-2.
7
A steric block in translation caused by the antibiotic spectinomycin.
ACS Chem Biol. 2007 Aug 17;2(8):545-552. doi: 10.1021/cb700100n. Epub 2007 Aug 10.
8
The antibiotic viomycin traps the ribosome in an intermediate state of translocation.
Nat Struct Mol Biol. 2007 Jun;14(6):493-7. doi: 10.1038/nsmb1243. Epub 2007 May 21.
9
Spontaneous reverse movement of mRNA-bound tRNA through the ribosome.
Nat Struct Mol Biol. 2007 Apr;14(4):318-24. doi: 10.1038/nsmb1221. Epub 2007 Mar 18.
10

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