Kotake Takeshi, Kosugi Satoru, Takimoto Takayuki, Nakata Soichi, Shiga Junko, Nagate Yasuhiro, Nakagawa Tsutomu, Take Hironori, Katagiri Shuichi
Department of Internal Medicine, Toyonaka Municipal Hospital, Toyonaka, Japan.
Intern Med. 2010;49(1):51-4. doi: 10.2169/internalmedicine.49.2774. Epub 2010 Jan 1.
We report a 39-year-old man with intravascular large B-cell lymphoma (IVLBCL) who had been treated as a case with pulmonary arterial hypertension (PAH) for one year. After he became worse, diffuse pulmonary (18)F-fluorodeoxyglucose (FDG) uptake in positron emission tomography (PET) suggested the existence of IVLBCL in the lung showing normal CT images. The diagnosis was confirmed with random transbronchial lung biopsy, and he was then successfully treated. Since IVLBCL presenting PAH has been rare and is difficult to diagnose, early application of FDG-PET may provide early recognition of the disorder, leading to a better outcome.
我们报告了一名39岁的血管内大B细胞淋巴瘤(IVLBCL)男性患者,该患者被误诊为肺动脉高压(PAH)并接受了一年的治疗。病情恶化后,正电子发射断层扫描(PET)显示肺部弥漫性(18)F-氟脱氧葡萄糖(FDG)摄取,而计算机断层扫描(CT)图像正常,提示肺部存在IVLBCL。经随机经支气管肺活检确诊后,患者得到了成功治疗。由于表现为PAH的IVLBCL较为罕见且难以诊断,早期应用FDG-PET可能有助于早期识别该疾病,从而获得更好的治疗效果。