Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Artif Organs. 2009 Nov;33(11):1032-7. doi: 10.1111/j.1525-1594.2009.00936.x.
Ventricular assist devices for small pediatric patients are expensive and commercially unavailable in Taiwan. We used the Medos ventricular assist device cannula (Medos, Aachen, Germany) and a centrifugal pump to support pediatric patients with dilated cardiomyopathy and decompensated heart failure. From January 2007 to December 2008, three pediatric patients with dilated cardiomyopathy were supported using a centrifugal pump as the left ventricular assist device. The Medos arterial cannula was sutured to the ascending aorta, and the Apex cannula was fixed into the left ventricular apex. When the patient was weaned off of cardiopulmonary bypass, the left ventricular assist device pump was started. The pump flow was gradually titrated according to the filling status of the left ventricle. All the left ventricular assist devices were successfully implanted and functioned well. Two patients on extracorporeal membrane oxygenation had severe lung edema before left ventricular assist device implantation. Both patients required extracorporeal membrane oxygenation for the postoperative period until the pulmonary edema was resolved. Among the three patients, two successfully bridged to heart transplantation after support for 6 and 11 days, respectively. The first patient (10 kg) expired due to systemic emboli 30 days after left ventricular assist device support. In summary, these results suggest that the Medos ventricular assist device cannula and a centrifugal pump is an option for temporary left ventricular assist device support in patients with intractable heart failure and as a bridge to heart transplantation.
台湾地区缺乏适用于小患儿的小型心室辅助装置,且价格昂贵。我们使用 Medos 心室辅助装置套管(德国亚琛 Medos 公司)和离心泵为患有扩张型心肌病和心力衰竭失代偿的儿科患者提供支持。2007 年 1 月至 2008 年 12 月,3 例扩张型心肌病患儿采用离心泵作为左心室辅助装置接受支持治疗。Medos 动脉套管缝合到升主动脉,尖端套管固定到左心室心尖部。当患者脱离体外循环时,启动左心室辅助装置泵。根据左心室充盈情况逐渐调整泵流量。所有左心室辅助装置均成功植入,功能良好。2 例接受体外膜氧合的患者在植入左心室辅助装置前存在严重肺水肿。这 2 例患者在术后均需要接受体外膜氧合治疗,直至肺水肿缓解。3 例患者中,2 例分别在支持 6 天和 11 天后成功桥接心脏移植。第 1 例(10 kg)在左心室辅助装置支持 30 天后因全身栓塞死亡。总之,这些结果表明,Medos 心室辅助装置套管和离心泵是治疗难治性心力衰竭患者的临时左心室辅助装置支持的一种选择,也可作为心脏移植的桥接。