Nucleus of Medicine and Experimental Surgery, School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.
ASAIO J. 2010 Jan-Feb;56(1):12-6. doi: 10.1097/MAT.0b013e3181c8444c.
The rotation of rollers in cardiopulmonary bypass pumps propels the blood through various devices to reach the patient. Very occlusive settings may squeeze red blood cells, whereas a nonocclusive setting may result in retrograde flow. Occlusion of roller pumps may be regulated either by measuring the drop rate or by dynamic calibration. This study evaluated the influence of silicone tubing residual stress found on pump regulation. Silicone tubes obtained from two different suppliers were used in 6-inch DeBakey roller pumps. The variations occurring over time in the measurements of drop rate, dynamic calibration, and tube residual stress were analyzed. Covariance analysis of the four linear regressions has shown a progressive and accentuated reduction in drop rate (p < 0.002). It is noticeable that the angular coefficients of the drop rate measurements of the four silicone tubes are the same (p > 0.56). This reduction in drop rate measurements may affect the regulation of the pumps before surgical procedures. One probable cause for this reduction is the residual stress found in the silicone tubes. Settings based on the dynamic calibration process tended to be repeated over time. Simple linear regression test (angular coefficient equals zero) has shown a p > 0.79 showing no interference of the silicone tubes residual stress on dynamic calibration, suggesting that one should use this method to calibrate roller pumps.
体外循环泵中的滚轮旋转推动血液通过各种设备到达患者。非常闭塞的设置可能会挤压红细胞,而非闭塞的设置可能会导致逆行流动。滚轮泵的阻塞可以通过测量下降率或通过动态校准来调节。本研究评估了在泵调节中发现的硅酮管残余应力的影响。从两个不同供应商处获得的硅酮管用于 6 英寸 DeBakey 滚轮泵。分析了下降率、动态校准和管残余应力测量随时间的变化。四个线性回归的协方差分析显示,下降率呈渐进性和明显降低(p<0.002)。值得注意的是,四个硅酮管的下降率测量的角度系数是相同的(p>0.56)。这种下降率测量的降低可能会影响手术前的泵调节。这种下降的一个可能原因是硅酮管中的残余应力。基于动态校准过程的设置往往会随着时间的推移而重复。简单线性回归测试(角度系数等于零)显示 p>0.79,表明硅酮管残余应力对动态校准没有干扰,这表明应该使用这种方法来校准滚轮泵。