Lador Frédéric, Beghetti Maurice, Rochat Thierry
Service de pneumologie, HUG, 1211 Genève 14.
Rev Med Suisse. 2009 Nov 18;5(226):2317-21.
Pulmonary arterial hypertension (PAH) is a rare clinical condition characterized by a progressive increase in pulmonary vascular resistance leading to right heart failure. The detection of this disease is limited by the accessibility of pulmonary vessels and rough initial symptoms, sometimes consisting only exertional dyspnea. In most cases, the patient presents a severe damage with a limited life expectancy at the time of diagnosis. This diagnosis, however, can be facilitated by the recognition of risk factors for the disease. The challenge of this early detection is to allow the establishment of a specific treatment which aims to improve the prognosis of patients by limiting the progression of the vasculopathy.
肺动脉高压(PAH)是一种罕见的临床病症,其特征是肺血管阻力逐渐增加,导致右心衰竭。这种疾病的检测受到肺血管可及性和初始症状不明显的限制,有时初始症状仅为劳力性呼吸困难。在大多数情况下,患者在诊断时已出现严重损害,预期寿命有限。然而,通过识别该疾病的危险因素可以促进诊断。早期检测面临的挑战是能够确立一种特异性治疗方法,旨在通过限制血管病变的进展来改善患者的预后。