Tang I P, Lee S C, Shashinder S, Raman R
ORL Department, Faculty of Medicine, University Malaysia Sarawak.
Med J Malaysia. 2009 Jun;64(2):155-8.
This is a retrospective study. The objective of this study is to review the factors influencing the outcome of treatment for the patients presented with idiopathic facial nerve paralysis. The demographic data, clinical presentation and management of 84 patients with idiopathic facial nerve paralysis (Bell's palsy) were collected from the medical record office, reviewed and analyzed from 2000 to 2005. Thirty-four (72.3%) out of 47 patients who were treated with oral prednisolone alone, fully recovered from Bell's palsy meanwhile 36 (97%) out of 37 patients who were treated with combination of oral prednisolone and acyclovir fully recovered. The difference was statistically significant. 42 (93.3%) out of 45 patients who presented within three days to our clinic, fully recovered while 28 (71.8%) out of 39 patients presented later then three days had full recovery from Bell's palsy. The difference was statistically significant. The outcome of full recovery is better with the patients treated with combined acyclovir and prednisolone compared with prednisolone alone. The patients who were treated after three days of clinical presentation, who were more than 50 years of age, who had concurrent chronic medical illness and facial nerve paralysis HB Grade IV to VI during initial presentation have reduced chance of full recovery of facial nerve paralysis.
这是一项回顾性研究。本研究的目的是回顾影响特发性面神经麻痹患者治疗结果的因素。从病历档案室收集了2000年至2005年期间84例特发性面神经麻痹(贝尔麻痹)患者的人口统计学数据、临床表现及治疗情况,并进行了回顾和分析。仅接受口服泼尼松龙治疗的47例患者中,有34例(72.3%)从贝尔麻痹中完全康复;而接受口服泼尼松龙与阿昔洛韦联合治疗的37例患者中,有36例(97%)完全康复。差异具有统计学意义。在发病三天内就诊于我们诊所的45例患者中,有42例(93.3%)完全康复;而在发病三天后就诊的39例患者中,有28例(71.8%)从贝尔麻痹中完全康复。差异具有统计学意义。与仅用泼尼松龙治疗相比,联合使用阿昔洛韦和泼尼松龙治疗的患者完全康复的结果更好。发病三天后接受治疗、年龄超过50岁、同时患有慢性疾病以及初诊时面神经麻痹HB分级为IV至VI级的患者,面神经麻痹完全康复的机会降低。