Batra Anjan S, Balaji Seshadri
Departments of Pediatric Cardiology, Children's Hospital of Orange County, University of California, Irvine, California.
Curr Cardiol Rev. 2009 Jan;5(1):40-4. doi: 10.2174/157340309787048167.
Cardiac Resynchronization therapy has become an important management tool in adults with heart failure and dilated cardiomyopathy. The role of CRT in children with CHF is still unclear. Evidence is slowly emerging in the pediatric cardiology literature that CRT may have an important and useful role in certain select populations with CHF. These include patients with complete heart block who develop pacing-induced cardiomyopathy, certain forms of congenital heart disease associated with systemic ventricular failure (even if the systemic ventricle is a morphologic RV) and in patients with idiopathic dilated cardiomyopathy. Studies in children supporting the use of CRT include many case reports, a few studies of CRT in post-operative patients, and one multi-center registry reporting the use of CRT in children. These papers will be summarized.
心脏再同步治疗已成为成人心力衰竭和扩张型心肌病的重要治疗手段。心脏再同步治疗在儿童心力衰竭中的作用仍不明确。儿科心脏病学文献中逐渐出现证据表明,心脏再同步治疗在某些特定的心力衰竭患儿群体中可能具有重要且有用的作用。这些群体包括发生起搏诱导性心肌病的完全性心脏传导阻滞患者、某些与体循环心室衰竭相关的先天性心脏病(即使体循环心室是形态学上的右心室)患者以及特发性扩张型心肌病患者。支持儿童使用心脏再同步治疗的研究包括许多病例报告、一些关于心脏再同步治疗在术后患者中的研究以及一项报告儿童使用心脏再同步治疗的多中心注册研究。这些论文将进行总结。