Takeuchi S, Takeda T, Saito H
Department of Otolaryngology, Kochi Medical School, Japan.
Ann Otol Rhinol Laryngol. 1991 Mar;100(3):244-8. doi: 10.1177/000348949110000314.
The pressure difference between the perilymph and the endolymph following infusion of artificial endolymph into the endolymphatic space was studied in guinea pigs. Both the perilymphatic and the endolymphatic pressures were measured simultaneously with use of two sets of a servo-nulling system. Endolymphatic infusion caused pressure increases in both the endolymphatic and the perilymphatic spaces, but no measurable pressure difference between them. Soon after the endolymphatic infusion, both pressures returned nearly to the initial levels. We conclude that 1) the endolymphatic and the perilymphatic pressures are very closely related, and 2) if a physiologically significant pressure difference exists between endolymph and perilymph in endolymphatic hydrops, it is below the resolving power of the methods used in this study (+/- 0.1 mm Hg).
在豚鼠身上研究了向内淋巴间隙注入人工内淋巴后外淋巴与内淋巴之间的压力差。使用两套伺服归零系统同时测量外淋巴压力和内淋巴压力。内淋巴注入导致内淋巴间隙和外淋巴间隙的压力均升高，但两者之间没有可测量的压力差。内淋巴注入后不久，两种压力几乎都恢复到初始水平。我们得出结论：1）内淋巴压力和外淋巴压力密切相关；2）如果在膜迷路积水的内淋巴和外淋巴之间存在具有生理意义的压力差，那么该压力差低于本研究中所用方法的分辨能力（±0.1 mmHg）。
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