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扩散张量成像在水平凝视麻痹和进行性脊柱侧凸中的进一步贡献。

Further diffusion tensor imaging contribution in horizontal gaze palsy and progressive scoliosis.

作者信息

Otaduy Maria Conceptión García, Leite Claudia da Costa, Nagae Lídia Mayumi, Pinho Marco da Cunha, Bueno Clarissa, Reed Umbertina Conti, Kok Fernando

机构信息

Department of Radiology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Arq Neuropsiquiatr. 2009 Dec;67(4):1054-6. doi: 10.1590/s0004-282x2009000600017.

Abstract

In two siblings with clinical diagnosis of horizontal gaze palsy associated with progressive scoliosis (HGPPS) we could demonstrate by diffusion tensor imaging: (1) An anterior displacement of the transverse pontine fibers; (2) Posterior clumping of the corticospinal, medial lemniscus and central tegmental tracts and of the medial and dorsal longitudinal fasciculi complex; (3) Absent decussation of superior cerebellar peduncle. Those findings can contribute as surrogate markers for the diagnosis.

摘要

在两名临床诊断为伴有进行性脊柱侧弯的水平凝视麻痹(HGPPS)的同胞中,我们通过扩散张量成像能够证实:(1)脑桥横纤维向前移位;(2)皮质脊髓束、内侧丘系和中央被盖束以及内侧和背侧纵束复合体向后聚集;(3)小脑上脚交叉缺失。这些发现可作为诊断的替代标志物。

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