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采用消融方式的微创外科手术治疗局限性肾肿瘤。

Minimally invasive surgery using ablative modalities for the localized renal mass.

机构信息

Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Int J Urol. 2010 Mar;17(3):215-27. doi: 10.1111/j.1442-2042.2009.02445.x. Epub 2009 Jan 7.

Abstract

Due to a number of evolving devices and modalities to treat the small, localized renal mass, the physician and patient have the opportunity to choose an appropriate therapy from several treatment options. Minimally invasive surgery to ablate a localized renal tumor is an alternative strategy to nephron-sparing surgery for the small renal mass. Even though partial nephrectomy has been established as an optimal technique for nephron-sparing surgery, patients who have comorbidities and renal insufficiency would potentially benefit from less invasive treatment. With respect to those concerns, several articles are discussed here regarding thermal ablative therapy for the small renal mass along with oncological outcomes and complications among these modalities compared to conventional procedures. In this review, a comprehensive PubMed search was conducted. For the purposes of reviewing the current status of thermal ablative modalities for the small renal mass, only articles written in English published from 1992 to 2009 were considered. Cryoablation and radiofrequency ablation are the most utilized and potentially promising therapies that are evolving as nephron-sparing minimally invasive surgery for patients with a localized renal tumor. High-intensity focused ultrasound, a relatively new modality to treat the renal mass, needs further study. All modalities require long-term follow up with unified reporting methods in terms of patient selection, pre- and post-treatment evaluation, treatment description, and analysis of outcome.

摘要

由于有许多不断发展的设备和方法来治疗小的局限性肾肿瘤,医生和患者有机会从几种治疗方案中选择合适的治疗方法。消融局限性肾肿瘤的微创手术是小肾肿瘤保肾手术的替代策略。虽然部分肾切除术已被确立为保肾手术的最佳技术,但患有合并症和肾功能不全的患者可能会受益于微创治疗。关于这些问题,本文讨论了一些关于小肾肿瘤热消融治疗的文章,以及与传统手术相比,这些方法在肿瘤学结果和并发症方面的情况。在这篇综述中,我们进行了全面的 PubMed 检索。为了回顾小肾肿瘤热消融治疗的现状,仅考虑了 1992 年至 2009 年期间用英文发表的文章。冷冻消融和射频消融是最常用和最有前途的治疗方法,随着保肾微创手术的发展,它们正在成为局限性肾肿瘤的治疗方法。高强度聚焦超声是一种治疗肾肿瘤的相对较新方法,需要进一步研究。所有方法都需要长期随访,并采用统一的报告方法,包括患者选择、治疗前后评估、治疗描述和结果分析。

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