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患有显著心律失常的英国激飞猎犬——临床表现、肌钙蛋白I及起搏器植入后的随访

English springer spaniels with significant bradyarrhythmias--presentation, troponin I and follow-up after pacemaker implantation.

作者信息

Fonfara S, Loureiro J F, Swift S, James R A, Pereira Y Martinez, Lopez-Alvarez J, Summerfield N, Dukes-McEwan J

机构信息

Small Animal Teaching Hospital, University of Liverpool, Neston, School of Veterinary Science, Leahurst Neston, UK.

出版信息

J Small Anim Pract. 2010 Mar;51(3):155-61. doi: 10.1111/j.1748-5827.2009.00867.x. Epub 2010 Jan 11.

Abstract

OBJECTIVES

English springer spaniels (ESS) are one of the most frequently presented breeds for pacemaker implantation in the UK and may do so at an early age. In comparison to dogs of other breeds (non-ESS) presenting for pacemaker implantation, cardiac troponin I (cTnI), the outcome and survival of ESS were investigated.

METHODS

Case records of dogs receiving pacemaker implantation were retrospectively reviewed.

RESULTS

Between September 2004 and October 2008, 58 dogs were presented to the Small Animal Teaching Hospital, University of Liverpool for pacemaker implantation. ESS (n=10) was the second most commonly presented breed. ESS were significantly younger than non-ESS (P=0.022). cTnI values were elevated on presentation and a significant reduction was present after pacemaker implantation (P=0.008) in all dogs. No significant difference in initial cTnI was identified comparing ESS and non-ESS (P=0.45) and median survival times were similar (P=0.37).

CLINICAL SIGNIFICANCE

ESS may be predisposed to bradyarrhythmias requiring pacemaker implantation. They present at a significantly younger age than non-ESS. Survival times between ESS and non-ESS were similar, despite ESS being paced at a younger age. However, pacemaker implantation is recommended in ESS, as median survival times of 30 months with a good quality of life were achieved.

摘要

目的

英国激飞猎犬(ESS)是英国接受起搏器植入手术最常见的犬种之一,且可能在幼年时就需要植入。与其他接受起搏器植入手术的犬种(非ESS)相比,对ESS的心肌肌钙蛋白I(cTnI)、手术结果及存活情况进行了研究。

方法

对接受起搏器植入手术的犬只病例记录进行回顾性分析。

结果

2004年9月至2008年10月期间,58只犬被送至利物浦大学小动物教学医院接受起搏器植入手术。ESS(n = 10)是第二常见的犬种。ESS比非ESS明显年轻(P = 0.022)。所有犬只在就诊时cTnI值均升高,起搏器植入后显著降低(P = 0.008)。比较ESS和非ESS,初始cTnI无显著差异(P = 0.45),中位生存时间相似(P = 0.37)。

临床意义

ESS可能易患需要起搏器植入的缓慢性心律失常。它们就诊时的年龄比非ESS明显小。尽管ESS在较年轻时就接受了起搏治疗,但ESS和非ESS的生存时间相似。然而,建议对ESS进行起搏器植入,因为其可实现30个月的中位生存时间且生活质量良好。

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