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特发性血小板减少性紫癜患者主动脉瓣连合处自发性撕裂所致主动脉瓣反流的修复

Repair of aortic regurgitation caused by spontaneous avulsion of aortic valve commissure in a patient with idiopathic thrombocytopenic purpura.

作者信息

Charokopos N, Artemiou P, Antonitsis P, Rouska E

机构信息

First Department of Thoracic and Cardiovascular Surgery, AHEPA Hospital, Thessaloniki, Greece.

出版信息

Thorac Cardiovasc Surg. 2010 Feb;58(1):43-4. doi: 10.1055/s-2008-1039057. Epub 2010 Jan 13.

Abstract

We describe a case of severe acute aortic regurgitation in a 60-year-old woman due to spontaneous avulsion of an aortic valve commissure. She presented with spontaneous bleeding and a platelet count of 4 000/microl caused by idiopathic thrombocytopenic purpura and developed acute heart failure and respiratory insufficiency. Preoperative transesophageal echocardiography was not diagnostic for the exact mechanism of aortic regurgitation. She received a 2-day course of intravenous immunoglobulin (0.5 mg/kg/d) to increase platelet count. At operation detachment (avulsion) of the commissure between the left and the right coronary cusp was evident. Aortic valve repair was performed with resuspension of the commissure. The postoperative course was uneventful. During a 24-month follow-up period, the patient has remained in NYHA class I.

摘要

我们描述了一例60岁女性因主动脉瓣连合处自发性撕脱导致严重急性主动脉瓣反流的病例。她因特发性血小板减少性紫癜出现自发性出血,血小板计数为4000/微升,并发展为急性心力衰竭和呼吸功能不全。术前经食管超声心动图未能明确诊断主动脉瓣反流的确切机制。她接受了为期2天的静脉注射免疫球蛋白疗程(0.5毫克/千克/天)以增加血小板计数。手术时可见左、右冠状动脉瓣叶之间连合处的分离(撕脱)。通过连合处重新悬吊进行了主动脉瓣修复。术后过程顺利。在24个月的随访期内,患者一直处于纽约心脏协会心功能I级。

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