Finsterbush A, Husseini N, Mann G, Shaul J
Orthopedic Dept., Hadassah-University Hospital, Mt. Scopus, Jerusalem.
Harefuah. 1991 Jan 15;120(2):62-6.
Jewish immigrants from Russia, and Arabs added to the population register since 1967, have a relatively high incidence of bone and joint tuberculosis. These patients now account for most of this disease in Israel. Skeletal tuberculosis imitates various joint conditions, most commonly, rheumatoid arthritis, and therefore presents a diagnostic problem. Injections of corticosteroids and/or immunosuppressive therapy can reactivate quiescent tuberculous lesions. During a 12-year period 14 patients with tuberculous arthritis involving 16 joints were seen in this hospital. They included 9 males and 5 females, 14-70 years old, 4 of whom were known to have had previous skeletal tuberculosis: 3 had spinal and 1 had hip involvement. None of the other 10 had a clinical history of tuberculosis, nor X-ray evidence of active pulmonary disease. 7 patients were diagnosed postoperatively as having joint tuberculosis on histopathological and bacteriological examination; 3 had positive cultures from joint aspirations. Most commonly involved were the spine and knee--4 cases of each. The wrist and acromioclavicular joint were affected in 2 cases each, and the hip, sacroiliac joint, ankle and elbow joints in 1 case each. The youngest patient, 14 years old, had triple-joint involvement of the wrist and the acromioclavicular and sacroiliac joints; the others had single-joint disease. In 1 patient the disease was reactivated after 36 years by surgical conversion of a fused hip to a mobile artificial joint. 3, whose joints were injected with corticosteroids, developed active, destructive tuberculous arthritis. A patient with rheumatoid arthritis who underwent total knee replacement was found to have active tuberculous arthritis.(ABSTRACT TRUNCATED AT 250 WORDS)
自1967年起被纳入人口登记的俄罗斯犹太移民以及阿拉伯人,骨与关节结核的发病率相对较高。如今,这些患者占以色列该国该疾病患者的大多数。骨结核会模仿多种关节病症,最常见的是类风湿性关节炎,因此存在诊断难题。注射皮质类固醇和/或免疫抑制疗法可使静止的结核病灶重新激活。在12年期间,本院共接诊了14例累及16个关节的结核性关节炎患者。其中包括9名男性和5名女性,年龄在14至70岁之间,其中4人已知既往有骨结核病史:3人脊柱受累,1人髋关节受累。其他10人既往均无结核病临床病史,也无活动性肺部疾病的X线证据。7例患者术后经组织病理学和细菌学检查诊断为关节结核;3例关节穿刺培养呈阳性。最常受累的部位是脊柱和膝关节,各有4例。腕关节和肩锁关节各有2例受累,髋关节、骶髂关节、踝关节和肘关节各有1例受累。最年轻的患者14岁,腕关节、肩锁关节和骶髂关节三联关节受累;其他患者为单关节疾病。1例患者在髋关节融合手术转换为可活动人工关节36年后,结核病情复发。3例关节注射皮质类固醇的患者发展为活动性、破坏性结核性关节炎。1例接受全膝关节置换的类风湿性关节炎患者被发现患有活动性结核性关节炎。(摘要截选至250字)