Tan-Kim Jasmine, Weinstein Milena M, Nager Charles W
Department of Reproductive Medicine, Division of Female Pelvic Medicine and Reconstructive Surgery, University of California, San Diego, La Jolla, CA, USA.
Int Urogynecol J. 2010 Jun;21(6):685-91. doi: 10.1007/s00192-009-1084-6. Epub 2010 Jan 14.
This study seeks to evaluate axial variation, comparisons with current technology, performance during dynamic conditions, and patient tolerability of the urethral sleeve sensor (USS) for maximal urethral closure pressure (MUCP) measurements.
Eighteen continent and seven stress incontinent women underwent assessments with USS and urethral pressure profilometry (UPP) in random order. Intravesical (p (ves)) and urethral (p (ura)) pressure signals were collected and urethral closure pressure (p (clo)) was calculated. A visual analog scale (VAS) was used to evaluate subject discomfort.
The correlation coefficient between MUCP obtained by UPP and USS techniques was 0.86 (p < 0.001). Higher USS pressures were obtained with catheter oriented to 12 o'clock. Continent subjects demonstrated higher values of p (clo). MUCP became <0 cm H(2)O in subjects with clinical leakage during Valsalva, but not in continent subjects. Subjects tolerated the USS technique better than the UPP technique on VAS (p < 0.001).
USS technology can be used to evaluate the urethra in both static and dynamic conditions and is better tolerated than withdrawal techniques.
本研究旨在评估尿道套传感器（USS）在测量最大尿道闭合压（MUCP）时的轴向变化、与当前技术的比较、动态条件下的性能以及患者耐受性。
18名控尿女性和7名压力性尿失禁女性随机先后接受了USS和尿道压力描记法（UPP）评估。收集膀胱内（p(ves)）和尿道（p(ura)）压力信号并计算尿道闭合压（p(clo)）。使用视觉模拟量表（VAS）评估受试者的不适程度。
UPP和USS技术测得的MUCP之间的相关系数为0.86（p<0.001）。导管指向12点时获得的USS压力更高。控尿受试者的p(clo)值更高。在Valsalva动作期间有临床漏尿的受试者中，MUCP<0 cm H₂O，但控尿受试者中并非如此。在VAS上，受试者对USS技术的耐受性优于UPP技术（p<0.001）。
USS技术可用于评估静态和动态条件下的尿道，且耐受性优于撤出技术。
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