College of Health Sciences, Korea University, Seoul, Korea.
J Toxicol Environ Health A. 2009;72(21-22):1484-92. doi: 10.1080/15287390903213061.
As a national project, obtaining information on the amount of heavy metal exposure of individuals through food intake is an important basic parameter for risk assessment. This study was conducted to evaluate dietary exposure levels and various risks from mercury (Hg) in Korean foods. In total, 342 samples comprising 114 food items were collected and then cooked prior to analysis. As found by Hg analysis, the mean content of metal in the fish and shellfish group was highest among the 15 Korean food groups. The total daily amount of Hg intake from typical Korean foods was 2.40 microg/person/d. The daily amount (microg/person/d) of Hg intake from each food group was 0.155 in grains and cereals, 0.008 potatoes and starch, 0.005 sugars and sweets, 0.0093 pulses, 0.0018 nuts and seeds, 0.203 vegetables, 0.027 fruits, 0.021 meats and poultry, 0.004 eggs, 1.826 fish and shellfish, 0.022 seaweed, 0.043 milk and dairy products, 0.008 oils and fats, 0.042 beverages, and 0.023 seasonings. The fish and shellfish group contributed most to total dietary intake at 76%. For risk assessment, probable daily intake (PDI) was calculated and compared with provisional tolerable weekly intake (PTWI) of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). The level of Hg intake through fish and shellfish of 0.001 mg/kg body weight bw/wk corresponded to 4.54% of the PTWI value of 0.005 mg/kg bw/wk, the safety standard for JECFA. The level of Hg intake through selected foods from the Food list for Koreans was 0.001 mg/kg bw/wk, corresponding to 5.95% of PTWI value. Therefore, overall intake was at levels below the recommended JECFA levels. The relative gender Hg hazard from Korean foods was 6.26% and 5.5% for males and females, respectively. The relative age Hg hazard from Korean foods was, 8.9% in those 3-6 yr old, 6.7% in those 7-12 yr old, 5.2% in those 13-19 yr old, 5.9% in those 20-29 yr old, 6.3% in those 30-49 yr old, 5.6% in those ages 50-64 yr, and 3.7% in the group of those over 65 yr of age. Relative regional Hg hazard from Korean foods was 6.3% in urban versus 5.5% in rural areas. Thus, the amount of Hg intake through consumption of Korean foods was found to be at a relatively safe level. These data may be thus used to establish safety standards for fish and shellfish consumption.
作为一项国家项目,通过食物摄入获取个体重金属暴露量的信息是风险评估的重要基础参数。本研究旨在评估韩国食品中汞(Hg)的膳食暴露水平和各种风险。总共采集了 342 个样本,包括 114 种食品,然后在分析前进行了烹饪。Hg 分析发现,15 种韩国食品组中鱼类和贝类组的金属含量最高。从典型的韩国食品中摄入的总汞日摄入量为 2.40 微克/人/天。从每个食品组摄入的汞日摄入量(微克/人/天)分别为谷物和谷物 0.155、土豆和淀粉 0.008、糖和甜食 0.005、豆类 0.0093、坚果和种子 0.0018、蔬菜 0.203、水果 0.027、肉类和家禽 0.021、鸡蛋 0.004、鱼类和贝类 1.826、海藻 0.022、牛奶和奶制品 0.043、油脂 0.008、饮料 0.042 和调味料 0.023。鱼类和贝类组对总膳食摄入量的贡献最大,为 76%。为了进行风险评估,计算了可能每日摄入量(PDI)并与食品添加剂联合专家委员会(JECFA)暂定每周耐受摄入量(PTWI)进行了比较。通过鱼类和贝类摄入的汞量为 0.001 毫克/千克体重 bw/wk,相当于 JECFA 安全标准 0.005 毫克/千克 bw/wk 的 4.54%。从韩国食品清单中选择的食物中摄入的汞量为 0.001 毫克/千克体重 bw/wk,相当于 PTWI 值的 5.95%。因此,总的摄入量低于 JECFA 建议的水平。来自韩国食品的男性和女性的相对性别 Hg 危害分别为 6.26%和 5.5%。来自韩国食品的相对年龄 Hg 危害在 3-6 岁的人群中为 8.9%,在 7-12 岁的人群中为 6.7%,在 13-19 岁的人群中为 5.2%,在 20-29 岁的人群中为 5.9%,在 30-49 岁的人群中为 6.3%,在 50-64 岁的人群中为 5.6%,在 65 岁以上的人群中为 3.7%。来自韩国食品的相对地区 Hg 危害在城市为 6.3%,在农村为 5.5%。因此,通过食用韩国食品摄入的汞量处于相对安全的水平。这些数据可用于制定鱼类和贝类消费的安全标准。