University of Bonn, Kekulé-Institute of Oganic Chemistry and Biochemistry, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.
Chemistry. 2010 Feb 22;16(8):2418-26. doi: 10.1002/chem.200902993.
Five racemic dissymmetric bis(pyridyl) ligands based on 2,8- or 3,9-difunctionalised Tröger's base derivatives have been synthesised. Only those derived from a 2,8-difunctionalised scaffold were found to undergo selective self-assembly to discrete self-assembled dinuclear metallosupramolecular aggregates of rhomboid shape upon coordination to cis-protected Pd(2+) or Pt(2+) ions, as evidenced by ESI mass spectrometry, NMR spectroscopy and single-crystal X-ray diffraction. Interestingly, these processes were found to be highly diastereoselective leading to the formation of C(2v)-symmetric heterochiral assemblies in a self-discriminating manner.
已经合成了五种基于 2,8-或 3,9-二官能化 Tröger's 碱衍生物的外消旋双（吡啶基）配体。只有那些衍生自 2,8-二官能化支架的配体被发现能够在与顺式保护的 Pd(2+)或 Pt(2+)离子配位时进行选择性自组装，形成离散的菱形形状的自组装双核金属超分子聚集体，这一点通过 ESI 质谱、NMR 光谱和单晶 X 射线衍射得到了证明。有趣的是，这些过程被发现具有高度的非对映选择性，导致以自区分的方式形成 C(2v)-对称的杂手性组装体。
