[1995 - 2006年杭州市健康人群百日咳 - 白喉 - 破伤风免疫水平观察]

[Observation of immunity level of pertussis-diphtheria-tetanus in healthy people in Hangzhou City during 1995-2006].

作者信息

Huang Li-Ming, Xu Er-Ping, Yang Luo-Xian

机构信息

Hangzhou City Center for Diseases Prevention and Control, Hangzhou 310006 Zhejiang, China.

出版信息

Zhongguo Yi Miao He Mian Yi. 2009 Feb;15(1):68-71.

PMID:20077681

Abstract

OBJECTIVE

To study the pertussis-diphtheria-tetanus immunity level of healthy people in Hangzhou.

METHODS

Pertussis antibody, diphtheria antitoxin and tetanus antitoxin were tested. We carried out surveillance in different counties among the people at 2-4, 6-8, 13-15, 25-39 age group during 1995-2006.

RESULTS

It showed that the pertussis antibody positive rate of 1942 persons was 93.87%, GMT 1: 1037.36 IU/ml, the antibody of people in countryside for the people at 2-4 age group was lower than that of other groups and the difference was significant compared with 6-8, 13-15 age group (chi2 = 8.80, 6.13, P < 0.01). The diphtheria antitoxin positive rate of 2141 persons was 91.59%, with the GMT was 0.2911 IU/ml. The tetanus antitoxin positive rate of 2141 persons was 72.35%, GMT 0.095 IU/ml.

CONCLUSIONS

We need to strengthen the EPI work in rural areas.

摘要

目的

研究杭州市健康人群百日咳-白喉-破伤风免疫水平。

方法

检测百日咳抗体、白喉抗毒素和破伤风抗毒素。于1995 - 2006年期间在不同县区对2 - 4岁、6 - 8岁、13 - 15岁、25 - 39岁年龄组人群进行监测。

结果

1942人百日咳抗体阳性率为93.87%，几何平均滴度（GMT）为1:1037.36 IU/ml，农村2 - 4岁年龄组人群抗体低于其他组，与6 - 8岁、13 - 15岁年龄组相比差异有统计学意义（χ² = 8.80，6.13，P < 0.01）。2141人白喉抗毒素阳性率为91.59%，GMT为0.2911 IU/ml。2141人破伤风抗毒素阳性率为72.35%，GMT为0.095 IU/ml。