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涉及瓣环的感染性心内膜炎的外科治疗

Surgical treatments for infective endocarditis involving valve annulus.

作者信息

Ishikawa Susumu, Kawasaki Akio, Neya Kazuo, Abe Keiko, Suzuki Haruo, Koizumi Satoko, Shibuya Hajime, Horikawa Masahiro, Ueda Keisuke

机构信息

Department of Surgery, Cardiovascular Division, Teikyo University School of Medicine, Tokyo, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 2009 Dec;15(6):378-81.

Abstract

OBJECTIVE

The early and late results of infective endocarditis (IE) with annular involvement were studied by focusing on surgical findings and operative procedures.

MATERIALS AND METHODS

Fifteen adult patients with a mean age of 56 years were reviewed. Eight had native valve endocarditis (NVE), and 7 had prosthetic valve endocarditis (PVE). The diseased valve was mitral in 6 patients, aortic in 8, and mitral plus aortic in 1. Twelve patients were operated on during the active phase of IE. Enterococcus, Staphyrococcus, Streptococcus, and Stenotrophomonaus Maltophilia were predominant in bacterial examination. The mean follow-up period was 37 months.

RESULTS

Active vegetation was observed in 63% of total patients. In NVE patients, valve replacement was performed in all 8 after complete debridement and annular patch reconstruction. One patient with hemodialysis died of heart failure. In PVE patients, valve deficiency was observed in all and active perivalvular abscess in 4. Conventional valve replacement was performed in 4 patients, and 3 of them died after surgery. Three patients who underwent aortic root translocation or Ross procedure survived. The hospital mortality of NVE and PVE surgery was 3% and 43%, respectively. There were no significant correlations between operative results and perioperative factors. During the follow-up period, late recurrent endocarditis did not occur, and one patient died of noncardiac diseases.

CONCLUSION

For NVE, good operative results were obtained after complete resection of infected valve annulus and valve replacement. For PVE, new surgical treatments, such as the translocation method or Ross procedure, should be induced for further improvement of surgical results.

摘要

目的

通过关注手术发现和手术操作,研究感染性心内膜炎(IE)合并瓣环受累的早期和晚期结果。

材料与方法

回顾了15例平均年龄56岁的成年患者。8例为自体瓣膜心内膜炎(NVE),7例为人工瓣膜心内膜炎(PVE)。病变瓣膜为二尖瓣6例,主动脉瓣8例,二尖瓣加主动脉瓣1例。12例患者在IE活动期接受手术。细菌检查中,肠球菌、葡萄球菌、链球菌和嗜麦芽窄食单胞菌占主导。平均随访期为37个月。

结果

63%的患者观察到活动性赘生物。在NVE患者中,8例均在彻底清创和瓣环补片重建后进行了瓣膜置换。1例接受血液透析的患者死于心力衰竭。在PVE患者中,均观察到瓣膜功能不全,4例有活动性瓣周脓肿。4例患者进行了传统瓣膜置换,其中3例术后死亡。3例接受主动脉根部移位或Ross手术的患者存活。NVE和PVE手术的医院死亡率分别为3%和43%。手术结果与围手术期因素之间无显著相关性。随访期间,未发生晚期复发性心内膜炎,1例患者死于非心脏疾病。

结论

对于NVE,在彻底切除感染的瓣环并进行瓣膜置换后可获得良好的手术效果。对于PVE,应采用新的手术治疗方法,如移位法或Ross手术,以进一步提高手术效果。

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