Ling Hui-Min, Wu Heng-Xuan, Huang Cui-Ye, Ma Shi-Qian
The 2nd People's Hospital of Qinzhou, Qinzhou 535000, Guangxi, China.
Zhongguo Gu Shang. 2009 Nov;22(11):859-61.
According to bone regeneration under the membrane and the bone regeneration deep fascia composite autologous red bone marrow transplantation applied in the treatment of fracture nonunion, in order to find a simple and effective clinical treatment of nonunion.
Since March 2006 to March 2009,17 patients of fracture nonunion were treated by the deep fascia composite autologous bone marrow transplantation,included 10 males and 7 females, aged from 7 to 52 years old (means 32 years). There were 10 cases of tibia, 5 cases of radius, 2 cases of clavicle. Injured to admission time was from 7 to 36 months (means 12 months). Ten cases underwent operation for 1 time,5 cases for twice and 2 cases for 3 times. The position of nonunion were all at bone shaft and the condition of the skin and soft tissue was good. X-ray film showed 11 cases of hyperplasia nonunion, 6 cases of shrinking. The original fixation were removed and the intramedullary nail or plate fixation were re-used, and fracture ends were sutured closed by autogenous deep fascia and implanted with autologous red bone marrow.
Seventeen patients were followed-up for from 5 months to 2 years with an average of 1 year. Fracture healing time was from 12 to 20 weeks (means 16 weeks). According to the criteria of fracture healing to assess efficacy, the results were excellent in 14 cases, good in 2 cases and poor in 1 case.
Deep fascia composite autologous autologous red bone marrow transplantation for the treatment of fracture nonunion is suitable at the bone shaft and good condition of skin and soft tissue. The method has been observed that the fracture healing time is short.
依据膜下骨再生及骨再生深筋膜复合自体红骨髓移植应用于骨折不愈合的治疗情况，探寻一种简单有效的骨折不愈合临床治疗方法。
自2006年3月至2009年3月，对17例骨折不愈合患者采用深筋膜复合自体骨髓移植治疗，其中男性10例，女性7例，年龄7至52岁（平均32岁）。胫骨骨折10例，桡骨骨折5例，锁骨骨折2例。受伤至入院时间为7至36个月（平均12个月）。10例患者接受1次手术，5例接受2次手术，2例接受3次手术。不愈合部位均在骨干，皮肤及软组织条件良好。X线片显示增生性不愈合11例，萎缩性6例。拆除原内固定，重新使用髓内钉或钢板固定，骨折端用自体深筋膜缝合封闭，并植入自体红骨髓。
17例患者随访5个月至2年，平均1年。骨折愈合时间为12至20周（平均16周）。根据骨折愈合标准评估疗效，结果优14例，良2例，差1例。
深筋膜复合自体红骨髓移植治疗骨折不愈合适用于骨干且皮肤及软组织条件良好的情况。观察发现该方法骨折愈合时间短。
