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[全球百日咳流行病学与免疫策略]

[Global pertussis epidemiology and immunization strategies].

作者信息

Zhang Wen-Hong

机构信息

Huashan Hospital, Fudan University, Shanghai 200040, China.

出版信息

Zhongguo Yi Miao He Mian Yi. 2009 Oct;15(5):467-72.

Abstract

Pertussis remains to be a global public health problem, even in developed countries with full coverage of universal vaccination. This has been accompanied by a change of disease epidemiology, characterized by a significant increase in reported pertussis cases among adolescents and adults. Actually, reported cases of pertussis represent only a small part of the whole pertussis cases reservoir. In response to the changing epidemiology, several countries have implemented booster programs of universal adolescent vaccine. In this paper, the anther tries to review the changing epidemiology and reveal the causes of resurgence. By comparing pertussis immunization schedules in different countries, it will be helpful for reconsidering the vaccination strategic for pertussis in our country.

摘要

百日咳仍然是一个全球公共卫生问题,即使在全面覆盖普遍接种疫苗的发达国家也是如此。这伴随着疾病流行病学的变化,其特征是青少年和成年人中报告的百日咳病例显著增加。实际上,报告的百日咳病例仅占整个百日咳病例库的一小部分。为应对不断变化的流行病学情况,一些国家实施了青少年普遍疫苗加强计划。在本文中,作者试图回顾流行病学的变化并揭示疫情复发的原因。通过比较不同国家的百日咳免疫接种计划,将有助于重新考虑我国百日咳的疫苗接种策略。

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