Gao Wu-Jun, Xie Lu, Lu Jing-Wen, Deng Chuan-Liang, Lu Long-Dou
College of Life Science, Henan Normal University, Xinxiang 453007, China.
Yi Chuan. 2010 Jan;32(1):25-30. doi: 10.3724/sp.j.1005.2010.00025.
Suppression of recombination is the prerequisite for plant sex chromosome evolution from a pair of autosomes. Recombination suppression around the locus controlling sex determination results in sex chromosome degeneration and differentiation. Important events such as repetitive sequence accumulation, heterochromatize, and DNA methylation have relation to recombination suppression. Accumulation of repetitive DNA sequence, including transposable elements and satellite DNA, leads to primitive sex chromosome differentiated on morphological and molecular structure, and also gives rise to chromosome heterochromatize, and thus recombination between sex chromosomes was suppressed. Here, we re-viewed the advances in this field, meanwhile, the function of DNA methylation in recombination suppression was analyzed.
重组抑制是植物性染色体从一对常染色体进化而来的前提条件。性别决定控制位点周围的重组抑制导致性染色体退化和分化。重复序列积累、异染色质化和DNA甲基化等重要事件与重组抑制有关。包括转座元件和卫星DNA在内的重复DNA序列的积累导致原始性染色体在形态和分子结构上分化,也导致染色体异染色质化,从而抑制了性染色体之间的重组。在此,我们回顾了该领域的进展,同时分析了DNA甲基化在重组抑制中的作用。