Taylor Rod S, Dalal Hayes, Jolly Kate, Moxham Tiffany, Zawada Anna
PenTAG, Peninsula Medical School, University of Exeter, Noy Scott House, Barrack Road, Exeter, UK, EX2 5DW.
Cochrane Database Syst Rev. 2010 Jan 20(1):CD007130. doi: 10.1002/14651858.CD007130.pub2.
The burden of cardiovascular disease world-wide is one of great concern to patients and health care agencies alike. Traditionally centre-based cardiac rehabilitation (CR) programmes are offered to individuals after cardiac events to aid recovery and prevent further cardiac illness. Home-based cardiac rehabilitation programmes have been introduced in an attempt to widen access and participation.
To determine the effectiveness of home-based cardiac rehabilitation programmes compared with supervised centre-based cardiac rehabilitation on mortality and morbidity, health-related quality of life and modifiable cardiac risk factors in patients with coronary heart disease.
We updated the search of a previous review by searching the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2007, Issue 4), MEDLINE, EMBASE and CINAHL from 2001 to January 2008. We checked reference lists and sought advice from experts. No language restrictions were applied.
Randomised controlled trials (RCTs) that compared centre-based cardiac rehabilitation (e.g. hospital, gymnasium, sports centre) with home-based programmes, in adults with myocardial infarction, angina, heart failure or who had undergone revascularisation.
Studies were selected independently by two reviewers, and data extracted by a single reviewer and checked by a second one. Authors were contacted where possible to obtain missing information.
Twelve studies (1,938 participants) met the inclusion criteria. The majority of studies recruited a lower risk patient following an acute myocardial infarction (MI) and revascularisation. There was no difference in outcomes of home- versus centre-based cardiac rehabilitation in mortality risk ratio (RR) was1.31 (95% confidence interval (C) 0.65 to 2.66), cardiac events, exercise capacity standardised mean difference (SMD) -0.11 (95% CI -0.35 to 0.13), as well as in modifiable risk factors (systolic blood pressure; diastolic blood pressure; total cholesterol; HDL-cholesterol; LDL-cholesterol) or proportion of smokers at follow up or health-related quality of life. There was no consistent difference in the healthcare costs of the two forms of cardiac rehabilitation.
AUTHORS' CONCLUSIONS: Home- and centre-based cardiac rehabilitation appear to be equally effective in improving the clinical and health-related quality of life outcomes in acute MI and revascularisation patients. This finding, together with an absence of evidence of difference in healthcare costs between the two approaches, would support the extension of home-based cardiac rehabilitation programmes such as the Heart Manual to give patients a choice in line with their preferences, which may have an impact on uptake of cardiac rehabilitation in the individual case.
心血管疾病在全球范围内的负担是患者和医疗保健机构都极为关注的问题之一。传统上,基于中心的心脏康复(CR)项目是在心脏事件发生后为个人提供的,以帮助康复并预防进一步的心脏疾病。家庭心脏康复项目已被引入,旨在扩大可及性和参与度。
比较家庭心脏康复项目与有监督的基于中心的心脏康复项目对冠心病患者死亡率、发病率、健康相关生活质量和可改变的心脏危险因素的有效性。
我们通过检索Cochrane图书馆(2007年第4期)中的Cochrane对照试验中心注册库(CENTRAL)、MEDLINE、EMBASE和CINAHL,对之前一篇综述的检索进行了更新,检索时间为2001年至2008年1月。我们检查了参考文献列表并向专家咨询。未设语言限制。
将基于中心的心脏康复(如医院、体育馆、体育中心)与家庭项目进行比较的随机对照试验(RCT),受试对象为患有心肌梗死、心绞痛、心力衰竭或接受过血管重建术的成年人。
由两位评审员独立选择研究,由一位评审员提取数据并由另一位进行核对。如有可能,会联系作者以获取缺失信息。
12项研究(1938名参与者)符合纳入标准。大多数研究招募的是急性心肌梗死(MI)和血管重建术后风险较低的患者。家庭心脏康复与基于中心的心脏康复在死亡率风险比(RR)为1.31(95%置信区间(CI)0.65至2.66)、心脏事件、运动能力标准化均数差(SMD)-0.11(95%CI -0.35至0.13)、可改变的危险因素(收缩压;舒张压;总胆固醇;高密度脂蛋白胆固醇;低密度脂蛋白胆固醇)或随访时吸烟者比例或健康相关生活质量方面,结果无差异。两种形式的心脏康复在医疗费用方面也没有一致的差异。
家庭心脏康复和基于中心的心脏康复在改善急性心肌梗死和血管重建术患者的临床及健康相关生活质量结果方面似乎同样有效。这一发现,再加上没有证据表明两种方法在医疗费用上存在差异,将支持扩展家庭心脏康复项目,如《心脏手册》,以便患者根据自己的偏好进行选择,这可能会影响个别病例中心脏康复的接受情况。