Takahashi S, Obinata D, Sakuma T, Matsui T, Takenobu Y, Igarashi T, Yoshizawa T, Sato K, Mochida J, Sugimoto S
Department of Urology, Nihon University School of Medicine, Tokyo, Japan.
Aktuelle Urol. 2010 Jan;41 Suppl 1:S20-3. doi: 10.1055/s-0029-1224661. Epub 2010 Jan 21.
We evaluated clinical efficacies of transvaginal mesh (TVM) reconstruction alone and those concomitant with a TVT/TOT sling for the treatment of pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Between January 2006 and February 2007, 138 female patients with POP underwent TVM reconstruction. The mean age was 66.6 years (range: 52-84). Fourteen individuals were qualified as grade II in the POP quantification (POP-Q) system, 85 and 39 were grades III and IV, respectively. One hundred and seventeen of 138 (85 %) cases showed SUI. Twenty-one patients without SUI underwent TVM alone, and 117 cases with SUI underwent TVM concomitant with TVT/TOT sling. Mean operation time and intra-operative bleeding was 79 min (range: 25-177) and 74 ml (range: 10-429), respectively. Mean follow-up period is 5.3 months (range: 1-14). The vaginal prolapses were cured (grade 0) in 129 cases (93 %) after the surgery. Total inter-national prostate symptom score (IPSS), its QOL score, International Consultation on Incontinence Questionnaires Short Form (ICIQ-SF) significantly improved (from 12.6 to 3.9; p < 0.0001, from 5.0 to 1.0; p < 0.0001, and from 6.1 to 2.5; p < 0.01, respectively). Six of 21 cases (29%) who underwent TVM alone showed postoperative de-novo SUI. In contrast, 116 cases (99%) who underwent TVM concomitant with TVT/TOT, experienced a cure of SUI. Maximum flow rate did not change postoperatively in the both groups. In conclusion, the short-term efficacies of TVM reconstruction for POP are excellent, and a concomitant TVT/TOT sling prevents postoperative SUI.
我们评估了单独经阴道网片(TVM)重建术以及TVM联合经阴道无张力尿道中段吊带术(TVT)/经闭孔无张力尿道中段吊带术(TOT)治疗盆腔器官脱垂(POP)和压力性尿失禁(SUI)的临床疗效。2006年1月至2007年2月,138例POP女性患者接受了TVM重建术。平均年龄为66.6岁(范围:52 - 84岁)。盆腔器官脱垂定量(POP-Q)系统中,14例为Ⅱ级,85例为Ⅲ级,39例为Ⅳ级。138例患者中有117例(85%)存在SUI。21例无SUI的患者仅接受TVM手术,117例有SUI的患者接受TVM联合TVT/TOT吊带术。平均手术时间和术中出血量分别为79分钟(范围:25 - 177分钟)和74毫升(范围:10 - 429毫升)。平均随访期为5.3个月(范围:1 - 14个月)。术后129例(93%)阴道脱垂治愈(0级)。国际前列腺症状评分(IPSS)总分、其生活质量评分、国际尿失禁咨询问卷简表(ICIQ-SF)均显著改善(分别从12.6降至3.9;p < 0.0001,从5.0降至1.0;p < 0.0001,从6.1降至2.5;p < 0.01)。仅接受TVM手术的21例患者中有6例(29%)术后出现新发SUI。相比之下,接受TVM联合TVT/TOT手术的116例患者(99%)SUI治愈。两组术后最大尿流率均无变化。总之,TVM重建术治疗POP的短期疗效极佳,联合TVT/TOT吊带术可预防术后SUI。