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一名65岁男性的膝关节结核性滑膜炎。

Tuberculous synovitis of the knee in a 65-year-old man.

作者信息

Ciobanu Laura D, Pesut Dragica P

机构信息

University of Medicine and Pharmacy Gr T Popa Iasi, Clinical Hospital of Rehabilitation Iasi, Romania.

出版信息

Vojnosanit Pregl. 2009 Dec;66(12):1019-22. doi: 10.2298/vsp0912019c.

Abstract

INTRODUCTION

Tuberculous (TB) synovitis is a rare, treatable, potentially lethal form of extrapulmonary TB resulting from massive lymphohematogenous dissemination of Mycobacterium tuberculosis (M. tuberculosis). We presented a case of TB synovitis of the knee in a Caucasian HIV-negative man from Romania, a high TB incidence country.

CASE REPORT

A 65-year old man presented with cough, high fever, mild wheezing, and swelling of the left knee. Chest radiography was normal. Sputum smears were Acid Fast Bacilli negative and Lowenstein-Jensen (L-J) culture negative for M. tuberculosis. Tuberculin skin test was negative. Respiratory symptoms disappeared in a week under antibiotics. Positive L-J cultures of knee punctation and favourable treatment outcome following standardized antituberculous treatment regimen confirmed the diagnosis of specific synovitis, which was also demonstrated by Magnetic Resonance Imaging (MRI).

CONCLUSION

Tuberculous synovitis is important differencial diagnosis in patients with arthropathies and risk factors for TB in all the countries and all patients' ages even when tuberculin skin test is negative.

摘要

引言

结核性滑膜炎是一种罕见的、可治疗但有潜在致命风险的肺外结核形式,由结核分枝杆菌大量经淋巴血行播散引起。我们报告了一例来自罗马尼亚(一个结核病高发国家)的白种人、HIV阴性男性的膝关节结核性滑膜炎病例。

病例报告

一名65岁男性出现咳嗽、高热、轻度喘息和左膝肿胀。胸部X线检查正常。痰涂片抗酸杆菌阴性,结核分枝杆菌罗氏培养阴性。结核菌素皮肤试验阴性。在抗生素治疗下,呼吸道症状在一周内消失。膝关节穿刺罗氏培养阳性,标准化抗结核治疗方案后治疗效果良好,证实为特异性滑膜炎,磁共振成像(MRI)也证实了这一点。

结论

在所有国家、所有年龄段的患者中,即使结核菌素皮肤试验阴性,结核性滑膜炎也是关节病患者和有结核病危险因素患者的重要鉴别诊断。

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