Department of Surgery, B. P. Koirala Institute of Health Sciences, Dharan 567O1, Koshi, Nepal.
Int J Surg. 2010;8(3):225-8. doi: 10.1016/j.ijsu.2009.11.016. Epub 2010 Jan 22.
The purpose of this study was to evaluate the clinical profile and outcome of patients with Hirschsprung's disease undergoing Soave's transabdominal pull-through.
The study is a prospective study in neonates, infants and children presenting to Surgery Department of B. P. Koirala Institute of Health Sciences, Dharan, Nepal with a diagnosis of Hirschsprung's disease who underwent a Soave's transabdominal pull-through from 2006 to 2008.
There were 20 patients, including 10 neonates (50%), 8 infants (40%) and 2 children (10%). There were 18 males and 2 females. Mean age at presentation was 9.2 months (range 7 days-7 years). Mean time of passing stool postoperatively was 49.5h (range 15-72h). Mean time to orally allowing was 97.2h postoperatively (range 36-120h). Mean hospital stay was 14.4 days (range 11-19days). One patient died due to uncontrollable hyperthermia (5% mortality). Other complications noted were 1(5.2%) anastomotic leak, 1(5.2%) cuff abscess and 1(5.8%) anastomotic stricture. Mean stool frequency at 1st month of follow-up was 6.8 per day, which later decreased to 4.5 per day at 3rd month, 3.1 per day at 6th month and 1.7 at 1 year. Two patients (11.7%) have constipation at 1 year follow-up.
The rate of complications like mortality, cuff abscess, anastomotic leak and constipation are comparable to other series. The short-term results of Soave's transabdominal pull-through have been satisfactory; however long-term results are still awaited.
本研究旨在评估行经腹 Soave 拖出术的先天性巨结肠患儿的临床特征和结局。
这是一项针对在尼泊尔 Dharan 的 B. P. Koirala 卫生科学研究所外科就诊并诊断为先天性巨结肠的新生儿、婴儿和儿童进行的前瞻性研究,这些患者在 2006 年至 2008 年期间接受了经腹 Soave 拖出术。
共有 20 名患者,包括 10 名新生儿(50%)、8 名婴儿(40%)和 2 名儿童(10%)。其中男 18 例,女 2 例。就诊时的平均年龄为 9.2 个月(7 天至 7 岁)。术后首次排便时间的平均时间为 49.5 小时(15-72 小时)。术后开始口服的平均时间为 97.2 小时(36-120 小时)。平均住院时间为 14.4 天(11-19 天)。1 例患者因无法控制的高热死亡(5%的死亡率)。其他并发症包括 1 例(5.2%)吻合口漏、1 例(5.2%)套管脓肿和 1 例(5.8%)吻合口狭窄。随访第 1 个月时的平均排便频率为每天 6.8 次,第 3 个月时减少至每天 4.5 次,第 6 个月时减少至每天 3.1 次,第 1 年时减少至每天 1.7 次。2 例患者(11.7%)在 1 年随访时出现便秘。
死亡率、套管脓肿、吻合口漏和便秘等并发症的发生率与其他系列相似。经腹 Soave 拖出术的短期结果令人满意,但仍需等待长期结果。