Ozer Necla, Deveci Onur Sinan, Okutucu Sercan, Demircin Metin
Department of Cardiology, Medicine Faculty of Hacettepe University, Ankara, Turkey.
Turk Kardiyol Dern Ars. 2009 Oct;37(7):479-82.
We present asymptomatic right atrial myxoma in a patient with breast ductal adenocarcinoma. A 58-year-old female was referred to our clinic for the evaluation of the potential cardiotoxic side effects of anthracycline-based chemotherapy. She had a 10-month history of modified radical mastectomy for ductal adenocarcinoma of the breast, followed by adjuvant chemotherapy. To evaluate potential side effects of anthracycline-based regimen, transthoracic echocardiography was performed, which showed a highly mobile, cystic, and heterogeneous mass, 20 x 25 mm in size, located in the right atrium. Transesophageal echocardiography confirmed the highly mobile mass originating from the inferior vena cava and extending to the right atrium. Surgery was planned. Upon exposure, the tumor had a broad base, with attachment to the lower dorsal free wall, interatrial septum of the right atrial cavity, and upper border of the inferior vena cava. The tumor was completely excised and histopathologic diagnosis was myxoma. Localization of right atrial myxoma at the junction of the inferior vena cava and right atrium is a rare condition, and its coexistence with breast carcinoma has only been reported once.
我们报告了一例患有乳腺导管腺癌的患者出现无症状性右房黏液瘤。一名58岁女性因评估蒽环类化疗潜在的心脏毒性副作用转诊至我院门诊。她有10个月前行乳腺导管腺癌改良根治术并随后接受辅助化疗的病史。为评估蒽环类化疗方案的潜在副作用,行经胸超声心动图检查,结果显示右房内有一大小为20×25mm、高度活动、囊性且不均匀的肿块。经食管超声心动图证实该高度活动的肿块起源于下腔静脉并延伸至右房。遂计划进行手术。术中见肿瘤基底较宽,附着于右房腔下后壁、房间隔及下腔静脉上缘。肿瘤被完整切除,组织病理学诊断为黏液瘤。右房黏液瘤位于下腔静脉与右房交界处的情况罕见,其与乳腺癌并存的情况仅曾有过一次报道。