罗特克角膜模块与海德堡视网膜断层扫描仪、欧卡斯 pentacam 和内皮细胞显微镜的数据比较。

Comparison of data from the rostock cornea module of the heidelberg retina tomograph, the oculus pentacam, and the endothelial cell microscope.

机构信息

Department of Ophthalmology and Eye Clinic, University of Leipzig, Leipzig, Germany.

出版信息

Cornea. 2010 Mar;29(3):314-20. doi: 10.1097/ICO.0b013e3181ac9e0d.

DOI:10.1097/ICO.0b013e3181ac9e0d

PMID:20098314

Abstract

PURPOSE

The aim of this study was to validate data arising from the Rostock Cornea Module (RCM) of the Heidelberg Retina Tomograph. Morphological parameters of the cornea were analyzed according to their dependency on patient's age.

METHODS

RCM measurements of 60 healthy eyes within 2 different age groups (group 1 <35 years, group 2 >50 years) were compared with the corneal thickness determined by the Oculus Pentacam and the endothelial cell density measured by the Tomey endothelial microscope, EM-2000.

RESULTS

The mean corneal thickness measured with the Heidelberg Retina Tomograph/RCM was 517 +/- 31 microm and 542 +/- 30 microm with the Oculus Pentacam (correlation coefficient, R = 0.78). Group 1 showed a corneal thickness of 509 +/- 24 microm with the RCM and 531 +/- 27 microm with the Pentacam. In group 2, the corneal thickness was 525 +/- 34 microm and 553 +/- 29 microm, respectively. A significant increase in corneal thickness for older patients could be shown. The differences between the methods and the age groups were statistically significant (P < 0.0001). The average endothelial cell density measured with the RCM was 2779 +/- 472 cells per square millimeter. Between the age groups and the methods (RCM and endothelial microscope), no statistically significant differences could be found. Cell densities for the epithelial cell layers and keratocytes showed no significant correlation with age and sex of the patients.

CONCLUSIONS

The RCM provides a reliable procedure for the evaluation of all corneal layers including morphological parameters. Endothelial cell densities either determined with the RCM or the EM-2000 are generally comparable to each other and showed no significant differences. It is suggested that lower corneal thickness measurements of the RCM can be caused by pressure during examination. An increased corneal thickness in the older group could be determined with the RCM and the Oculus Pentacam.

摘要

目的

本研究旨在验证海德堡视网膜断层扫描仪（RCM）罗斯托克角膜模块得出的数据。根据患者年龄，分析角膜形态参数。

方法

将 60 例健康眼分为 2 个年龄组（组 1<35 岁，组 2>50 岁），分别与 Oculus Pentacam 测定的角膜厚度和 Tomey 内皮显微镜（EM-2000）测量的内皮细胞密度进行比较。

结果

与 Oculus Pentacam（相关系数 R=0.78）相比，RCM 测量的平均角膜厚度为 517±31μm和 542±30μm。组 1 的 RCM 角膜厚度为 509±24μm，Pentacam 为 531±27μm。组 2 的角膜厚度分别为 525±34μm和 553±29μm。可显示老年患者的角膜厚度明显增加。不同方法和年龄组之间的差异具有统计学意义（P<0.0001）。RCM 测量的平均内皮细胞密度为 2779±472 个细胞/平方毫米。在年龄组和方法（RCM 和内皮显微镜）之间，未发现统计学上的显著差异。上皮细胞层和角膜细胞的细胞密度与患者的年龄和性别无显著相关性。