Stieler W, Mensing H, Schaeg G, Jehn E
Hautklinik, Klinikums Minden.
Hautarzt. 1991 Jan;42(1):44-7.
Primary leiomyosarcomas of the superficial soft tissues are very rare neoplasms. Because of the different biological behaviour, they should be divided into cutaneous and subcutaneous tumours. Differential diagnosis includes leiomyomas, skin metastases from extracutaneous leiomyosarcomas, and other spindle-cell tumours of the skin. Ultrastructural and immunohistochemical investigations are useful when light microscopic features do not allow an unequivocal diagnosis. Although local recurrences develop in almost half the patients with cutaneous leiomyosarcomas, the prognosis is predominantly good. In contrast, metastatic spread is more common in patients with subcutaneous leiomyosarcomas. Treatment for superficial leiomyosarcomas consists in wide excision. We report on a 76-year-old women with a local recurrence of a primary cutaneous leiomyosarcoma.
浅表软组织原发性平滑肌肉瘤是非常罕见的肿瘤。由于其生物学行为不同,应分为皮肤和皮下肿瘤。鉴别诊断包括平滑肌瘤、皮肤外平滑肌肉瘤的皮肤转移以及其他皮肤梭形细胞肿瘤。当光镜特征不能明确诊断时,超微结构和免疫组化检查很有用。虽然几乎一半的皮肤平滑肌肉瘤患者会出现局部复发,但预后总体良好。相比之下,皮下平滑肌肉瘤患者发生转移更为常见。浅表平滑肌肉瘤的治疗方法是广泛切除。我们报告了一例76岁女性原发性皮肤平滑肌肉瘤局部复发的病例。