Laboratoire de Spectrométrie de Masse et de Chimie Laser, Institut Jean Barriol-Fédération de Recherche 2843, Université Paul Verlaine-Metz, 1, Boulevard Arago, F-57078 Metz, Technopole Cedex 03, France.
Anal Chim Acta. 2010 Feb 5;659(1-2):34-54. doi: 10.1016/j.aca.2009.11.047. Epub 2009 Dec 3.
Laser-based aerosol mass spectrometry in both on-line and off-line modes has become an essential tool to analyze airborne and industrial dust particles. The versatility of laser desorption and/or ionization appears to be a powerful tool to obtain the global composition of environment particles. Laser mass spectrometry to analyze inorganic (elemental and molecular), organic and biological aerosol components without or with a restricted number of preparation steps in both on-line and off-line modes can be regarded as an ideal analytical machine. However, some limitations are associated to this range of mass spectrometry techniques. This review presents the fundamental aspects of laser-based mass spectrometry and the different kinds of analyses, which may be done. A selected number of applications are then given which allows the reader to consider both the capabilities and the drawbacks of laser mass spectrometry to analyze dust environmental particles. Critical discussion is focused on comparison and new trends of these aerosol analytical techniques.
基于激光的气溶胶质谱分析，无论是在线还是离线模式，已经成为分析空气中和工业粉尘颗粒的重要工具。激光解吸和/或电离的多功能性似乎是获得环境颗粒整体成分的有力工具。激光质谱分析可以在在线和离线模式下，对无机（元素和分子）、有机和生物气溶胶成分进行无预处理或有限数量预处理的分析，这可以被视为一种理想的分析仪器。然而，这种质谱分析技术也存在一些局限性。本综述介绍了基于激光的质谱分析的基本原理和可以进行的不同类型的分析。然后给出了一些选定的应用实例，使读者能够考虑激光质谱分析粉尘环境颗粒的能力和缺点。批判性讨论集中在这些气溶胶分析技术的比较和新趋势上。
