不明原因发热：一家中国三级医院的 142 例病例再探讨。

Fever of unknown origin: revisit of 142 cases in a tertiary Chinese hospital.

机构信息

Department of Infectious Diseases, Huashan Hospital Af fi liated to Fudan University, Shanghai, China.

出版信息

Biosci Trends. 2008 Feb;2(1):44-6.

PMID:20103898

Abstract

To investigate the causes of fever of unknown origin (FUO), we analyzed the clinical data on 142 patients with FUO admitted to our department from January 2002 to December 2003. After various examinations and specific treatment, a definitive diagnosis was reached in 122 cases. Of them, 51 cases (35.9%) were caused by infections, 46 (32.4%) were due to autoimmune diseases, 18 (12.7%) were due to tumors, 7 (4.9%) were due to other diseases, and in 20 (14.1%) the cause was still unknown after hospitalization. In conclusion, infection is the main cause of FUO. Autoimmune diseases and malignant tumors are both significant causes. Most patients with an FUO were ultimately diagnosed with various examinations and careful analysis.

摘要

为了探讨不明原因发热（FUO）的病因，我们分析了 2002 年 1 月至 2003 年 12 月我院收治的 142 例 FUO 患者的临床资料。经过各种检查和特异性治疗，122 例患者获得明确诊断。其中，51 例（35.9%）由感染引起，46 例（32.4%）由自身免疫性疾病引起，18 例（12.7%）由肿瘤引起，7 例（4.9%）由其他疾病引起，20 例（14.1%）住院后病因仍未明。总之，感染是 FUO 的主要病因，自身免疫性疾病和恶性肿瘤也是重要病因。大多数 FUO 患者经各种检查和仔细分析后最终获得明确诊断。