Transplant Services, Balboa Nephrology Medical Group, Inc., San Diego, CA, USA.
Clin Transplant. 2010 Jul-Aug;24(4):572-7. doi: 10.1111/j.1399-0012.2010.01208.x.
We studied the impact of a first post-transplant cytomegalovirus (CMV) infection greater than one year after primary kidney transplantation. Risk factors for developing late CMV were acute rejection and donor-recipient CMV status. Of those developing late CMV, 35% were donor (D) positive, recipient (R) negative; however, 23% were D+R+, 22% D-R+, and 15% D-R-. Late CMV was associated with significantly decreased patient and graft survival.
我们研究了原发性肾移植后一年以上初次移植后巨细胞病毒(CMV)感染的影响。发生晚期 CMV 的危险因素是急性排斥反应和供受者 CMV 状态。在发生晚期 CMV 的患者中,35%为供体(D)阳性,受体(R)阴性;然而,23%为 D+R+,22%为 D-R+,15%为 D-R-。晚期 CMV 与患者和移植物存活率显著降低相关。