Ferrete-Morales C, Vázquez-Pérez M A, Sánchez-Berna M, Gilabert-Cerro I, Corzo-Delgado J E, Pineda-Vergara J A, Vergara-López S, Gómez-Mateos J
Unidad de Enfermedades Infecciosas, Hospital Universitario de Valme, Sevilla, España.
Enferm Clin. 2010 Jan-Feb;20(1):3-9. doi: 10.1016/j.enfcli.2009.10.001. Epub 2010 Jan 27.
To assess the impact on the incidence of PPIVC by implementing a catheter management protocol and to determine risk factors for PPIVC development in hospitalized patients.
A total of 3978 episodes of venous catheterization were prospectively included from September 2002 to December 2007. A catheter management protocol was implemented during this period of time. The incidence and variables associated to the occurrence of PPIVC were determined.
The incidence of PPIVC from 2002 to 2007 was 4.8%, 4.3%, 3.6%, 2.5%, 1.3% and 1.8% (p<0.001). Perfusion of amiodarone [adjusted OR (AOR) 25.97; 95% CI=7.29-92.55, p=0.0001] and cefotaxime (AOR 2.90; 95% CI=1.29-6.52, p=0.01) and the shift when the catheters were placed (AOR for morning vs. night shift 0.60; 95% CI=0.35-1.02, p=0.063) were independently associated to the development of PPIVC. A history of phlebitis was the only factor independently associated to phlebitis due to peripherally inserted central venous catheters (AOR 3.24; CI at 95% CI= 1.05-9.98, p=0.04).
A catheter management protocol decreases the incidence of PPIVC in hospitalized patients. The risk of PPIVC increases for peripherally inserted central venous catheters when the patients have a history of phlebitis and for peripheral venous catheters when amiodarone or cefotaxime are infused. Catheterization of peripheral veins performed during morning shifts is associated with a lower incidence of PPIVC when compared with night shift catheterizations.
评估实施导管管理方案对周围静脉导管相关静脉炎(PPIVC)发生率的影响,并确定住院患者发生PPIVC的危险因素。
前瞻性纳入2002年9月至2007年12月期间共3978例静脉置管病例。在此期间实施导管管理方案。确定PPIVC发生的发生率及相关变量。
2002年至2007年PPIVC的发生率分别为4.8%、4.3%、3.6%、2.5%、1.3%和1.8%(p<0.001)。输注胺碘酮[校正比值比(AOR)25.97;95%可信区间(CI)=7.29 - 92.55,p = 0.0001]和头孢噻肟(AOR 2.90;95%CI = 1.29 - 6.52,p = 0.01)以及置管时的班次(早班与夜班相比的AOR为0.60;95%CI = 0.35 - 1.02,p = 0.063)与PPIVC的发生独立相关。静脉炎病史是外周静脉置入中心静脉导管所致静脉炎的唯一独立相关因素(AOR 3.24;95%CI = 1.05 - 9.98,p = 0.04)。
导管管理方案可降低住院患者PPIVC的发生率。有静脉炎病史的患者使用外周静脉置入中心静脉导管时PPIVC风险增加,输注胺碘酮或头孢噻肟时使用外周静脉导管PPIVC风险增加。与夜班置管相比,早班进行外周静脉置管时PPIVC的发生率较低。