鉴定来自约旦的人类分离株中罕见和新型隐孢子虫 GP60 亚型。
Identification of rare and novel Cryptosporidium GP60 subtypes in human isolates from Jordan.
机构信息
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, The Hashemite University, P.O. Box 150459, Zarqa 13115, Jordan.
出版信息
Exp Parasitol. 2010 Jun;125(2):161-4. doi: 10.1016/j.exppara.2010.01.011. Epub 2010 Jan 28.
Little is known about the epidemiology of Cryptosporidium in Jordan and no genotyping studies have been conducted on Cryptosporidium isolates from humans or animals from Jordan. Genotyping of 44 Cryptosporidium isolates from Jordanian children at the 18S rRNA locus and a unique diagnostic locus identified four Cryptosporidium species; C. parvum (22), C. hominis (20), C. meleagridis (1) and C. canis (1). Sub-genotype analysis of 29 isolates at the 60-kDa glycoprotein (GP60) locus identified three C. parvum, two C. hominis subtype families and one C. meleagridis subtype. Several rare and novel subtypes were identified indicating unique endemicity and transmission of Cryptosporidium in Jordan.
关于约旦的隐孢子虫流行病学知之甚少，也没有对来自约旦人类或动物的隐孢子虫分离株进行基因分型研究。对来自约旦儿童的 44 个隐孢子虫分离株在 18S rRNA 基因座和独特的诊断基因座进行基因分型，鉴定出了 4 种隐孢子虫；小隐孢子虫（22）、人隐孢子虫（20）、鸸鹋隐孢子虫（1）和犬隐孢子虫（1）。对 29 个分离株在 60kDa 糖蛋白（GP60）基因座的亚基因型分析鉴定出 3 种小隐孢子虫、2 种人隐孢子虫亚型家族和 1 种鸸鹋隐孢子虫亚型。鉴定出了一些罕见和新型的亚型，表明在约旦存在独特的隐孢子虫地方性流行和传播。
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