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肿胀麻醉吸脂术:下眼睑局部利多卡因低剂量(400mg/L)的疗效。

Tumescent liposuction: efficacy of a lower lidocaine dose (400 mg/l).

机构信息

White House Center for Liposuction, Zürich, Switzerland. info @ whitehousecenter.ch

出版信息

Dermatology. 2010;220(3):223-5. doi: 10.1159/000277624. Epub 2010 Jan 29.

Abstract

BACKGROUND

Local anesthesia has been widely accepted as the standard of care in liposuction. Anesthesia is achieved with a standard tumescent solution, and lidocaine is most often used at a concentration of 500 mg/l.

OBJECTIVE

To evaluate the efficacy of a 400 mg/l lidocaine concentration in tumescent liposuction.

METHODS

We performed a randomized clinical trial on 200 consecutive patients undergoing lipoaspiration. Patients were divided into two groups: group A (n = 100) received tumescent solution with a lidocaine concentration of 500 mg/l, in group B (n = 100) lidocaine levels were reduced to 400 mg/l. Pain was assessed twice during the procedure, at infiltration and while liposuction was performed. Patients rated their pain level on a numeric rating scale from 0 to 10, with 10 being the worst possible pain.

RESULTS

Tumescent solution containing a lidocaine concentration of 400 mg/l provided effective local anesthesia during lipoaspiration. There was no statistically significant difference in the pain level between the two groups.

CONCLUSION

We propose the use of a lower lidocaine concentration of 400 mg/l in the tumescent solution compared to the originally described solution containing 500 mg/l. This is of particular interest when multiple body parts or larger areas are to be treated to avoid lidocaine toxicity.

摘要

背景

局部麻醉已被广泛接受为吸脂术的标准护理。麻醉是通过标准肿胀溶液实现的,利多卡因最常以 500mg/L 的浓度使用。

目的

评估 400mg/L 利多卡因浓度在肿胀吸脂术中的疗效。

方法

我们对 200 例连续接受吸脂术的患者进行了随机临床试验。患者分为两组:A 组(n=100)接受利多卡因浓度为 500mg/L 的肿胀溶液,B 组(n=100)将利多卡因水平降低至 400mg/L。在手术过程中两次评估疼痛,在浸润时和吸脂时进行。患者在 0 到 10 的数字评分量表上对疼痛程度进行评分,其中 10 为最严重的疼痛。

结果

含有 400mg/L 利多卡因的肿胀溶液在吸脂术中提供了有效的局部麻醉。两组之间的疼痛水平没有统计学上的显著差异。

结论

我们建议在肿胀溶液中使用较低的利多卡因浓度 400mg/L,与最初描述的含有 500mg/L 利多卡因的溶液相比。当需要治疗多个身体部位或更大面积时,这一点尤其有趣,以避免利多卡因毒性。

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