Department of Minimal Access Surgery, Apollo Hospital, Sarita Vihar, New Delhi 110044, India.
Surg Endosc. 2010 Aug;24(8):1952-7. doi: 10.1007/s00464-010-0885-5. Epub 2010 Jan 29.
Primary hyperhidrosis is a disorder that is characterized by excessive sweating in disproportion to that required for thermoregulation. In most cases, this is aggravated by emotional factors and by heat. Hyperhidrosis can be seen in the palms of the hands, armpits, soles of the feet and face. The principal characteristic of this disease is the intense discomfort of patients, which affects their social and professional life. Treatment modalities include topical application of aluminum chloride, iontophoresis, anticholinergics, botulinum toxin injection, liposuction, excision of sweat glands, and thoracic sympathectomy.
Between January 1998 and August 2007, a prospective study of endoscopic thoracic sympathectomies for palmar hyperhidrosis was undertaken based on case histories and a prospective pre- and postoperative questionnaire survey. The sample comprised of 322 patients with a mean age of 24 years. At Apollo Hospital, New Delhi, India, bilateral video-assisted thoracoscopic T3 level sympathectomies were performed in all cases.
All patients had immediate cessation of palmar hyperhidrosis. The mean postoperative stay was 1.1 days. A questionnaire was completed based on their response to a telephone conversation or e-mail. A paired t test and Wilcoxon test was performed on these data and it showed significant improvement in quality of life. Compensatory sweating was found to be the most troublesome side effect for all patients. It was seen in 63% of the patients. This is similar to other reports of compensatory sweating; however, the figure decreases to 29% if we disregard the percentage of patients who reported only mild compensatory sweating.
In view of the low morbidity and zero mortality rate of this surgical technique, we recommend it as a method of treatment for palmar hyperhidrosis. Thoracic sympathectomy eliminates palmar hyperhidrosis with minimal recurrence (1% in our series) and produces a high rate of patient satisfaction.
原发性多汗症是一种以与体温调节不成比例的过度出汗为特征的疾病。在大多数情况下,这种情况会因情绪因素和热量而加重。多汗症可发生在手的手掌、腋窝、脚底和面部。这种疾病的主要特征是患者极度不适,影响他们的社交和职业生活。治疗方法包括氯化铝局部应用、离子电渗疗法、抗胆碱能药物、肉毒杆菌毒素注射、吸脂术、汗腺切除术和胸腔交感神经切除术。
1998 年 1 月至 2007 年 8 月,根据病史和前瞻性术前和术后问卷调查,对 322 例手掌多汗症患者进行了胸腔镜交感神经切除术的前瞻性研究。样本包括 322 例平均年龄为 24 岁的患者。在印度新德里阿波罗医院,所有患者均行双侧视频辅助胸腔镜 T3 水平交感神经切除术。
所有患者手掌多汗症均立即停止。平均术后住院时间为 1.1 天。根据他们对电话交谈或电子邮件的回复完成了一份问卷。对这些数据进行了配对 t 检验和 Wilcoxon 检验,结果显示生活质量有显著改善。代偿性出汗被发现是所有患者最麻烦的副作用。63%的患者出现这种情况。这与其他代偿性出汗的报告相似;然而,如果我们忽略报告仅轻度代偿性出汗的患者的百分比,则该数字下降到 29%。
鉴于这种手术技术的发病率低且死亡率为零,我们建议将其作为手掌多汗症的治疗方法。胸腔交感神经切除术可消除手掌多汗症,复发率低(我们系列中的 1%),且患者满意度高。