Quesada-Vazquez A J, Contreras-Maure L J, Traba-Tamayo E R, Frometa-Guerra A
Hospital General Universitario Carlos Manuel de Cespedes, Bayamo, Cuba.
Rev Neurol. 2010;50(2):72-6.
To identify the clinical-epidemiological features and the factors related to the presence of disability in patients with migraine.
A cross-sectional study was conducted in a rural population at the Policlinica Mabay in the province of Granma, Cuba. The second International Headache Society classification was used. Sample size, which was calculated using the program EpiInfo 2002, was 360 adult workers over 18 years of age, who were selected by simple random sampling.
Sixty-one respondents were diagnosed with migraine (prevalence: 16.9%; 95% CI = 13.3-21.31). Prevalence among females was 24.3% (CI 95% = 18.7-30.82) and 7.1% (CI 95% = 3.8-12.73) among males. Chronic migraine was the most frequent, with 25 cases (prevalence: 6.9%; CI 95% = 4.63-10.21), followed by migraine without aura, with 18 diagnoses (prevalence: 5%; CI 95% = 3.08-7.93). Frequency of headaches was greater in females (30.17 Y 12 days versus 23.45 Y 10 days; p = 0.041), as was their duration (19.87 Y 6.95 h versus 15.73 Y 5.58 h in males; p = 0.027). Minimal disability affected 24.6% of patients with migraine and 39.3% suffered moderate disability. Higher degrees of disability were associated to being female, the time elapsed since onset of the disease (21.04 Y 10.1 years versus 15.33 Y 7.5 years; p = 0.017), the frequency of headaches in the last three months (30.28 Y 10.1 days with headache versus 25.25 Y 8.5; p = 0.042), the duration of the headache (23.3 Y 15.24 h versus 12.38 Y 10.9 h; p = 0.002) and chronic migraine (p = 0.016).
There is a great social and occupational burden of disability in patients with migraine in the geographical area under study, and females are affected by this condition to a greater extent.
确定偏头痛患者的临床流行病学特征以及与残疾存在相关的因素。
在古巴格拉玛省马拜综合诊所的农村人口中进行了一项横断面研究。采用了国际头痛协会的第二版分类标准。使用EpiInfo 2002程序计算样本量,为360名18岁以上的成年工人,通过简单随机抽样选取。
61名受访者被诊断为偏头痛(患病率:16.9%;95%可信区间 = 13.3 - 21.31)。女性患病率为24.3%(95%可信区间 = 18.7 - 30.82),男性为7.1%(95%可信区间 = 3.8 - 12.73)。慢性偏头痛最为常见,有25例(患病率:6.9%;95%可信区间 = 4.63 - 10.21),其次是无先兆偏头痛,有18例诊断(患病率:5%;95%可信区间 = 3.08 - 7.93)。女性头痛频率更高(30.17 ± 12天对比23.45 ± 10天;p = 0.041),头痛持续时间也是如此(男性为19.87 ± 6.95小时对比15.73 ± 5.58小时;p = 0.027)。轻度残疾影响了24.6%的偏头痛患者,39.3%的患者有中度残疾。更高程度的残疾与女性、疾病发作后的时间(21.04 ± 10.1年对比15.33 ± 7.5年;p = 0.017)、过去三个月的头痛频率(有头痛的为30.28 ± 10.1天对比25.25 ± 8.5天;p = 0.042)、头痛持续时间(23.3 ± 15.24小时对比12.38 ± 10.9小时;p = 0.002)以及慢性偏头痛(p = 0.016)相关。
在所研究的地理区域,偏头痛患者存在巨大的社会和职业残疾负担,且女性受此疾病影响的程度更大。