Wang Hui-Yan, Duan Xin, Chen Ying, Li Jian
Department of Orthopaedics, the West China Hospital Affiliated to Sichuan University, Chengdu 610041, Sichuan, China.
Zhongguo Gu Shang. 2009 Dec;22(12):910-2.
To observe the bacterial characteristic of orthopedic open wounds injured in Wenchuan earthquake and their drug-resistant pattern for reasonable application of antibiotics.
A total of 340 secretion specimens isolated from 148 cases of orthopedic open wounds of earthquake victims were analyzed. Among the patients, 71 patients were male and 77 patients were female, ranging in age from 2 to 82 years, with an average of 40.4 years. Thirty-seven patients were detained under the ground ranged from 5 min to 102 h. The 340 specimens of exudation in the wound were collected for bacterial culture and drug sensitivity tests.
The infection rate of 148 cases was 66.2 percent. Two hundred and fifty-seven pathogens were isolated from 340 secretion specimen, including gram-negative bacteria accounted for 77.8%, gram-positive bacteria accounted for 20.6%. The most frequent pathogens isolated from secretion culture in Wenchuan earthquake survivors were Escherichia coli (16.3%), Acinetobacter baumannii (16.0%), Staphylococcus aureus (13.6%), Pseudomonas aeruginosa (12.5%) and Enterobacter cloacae (8.6%).
The drug sensitivity test of exudation as well as exact application of antibiotics should be highly payed attention to by doctors in order to reduce the occurrence of bacterial resistance.
观察汶川地震所致骨科开放性伤口的细菌学特点及其耐药模式,以合理应用抗生素。
对148例地震伤员骨科开放性伤口分离出的340份分泌物标本进行分析。患者中,男性71例,女性77例,年龄2至82岁,平均40.4岁。37例被埋于地下5分钟至102小时。采集340份伤口渗出物标本进行细菌培养及药敏试验。
148例感染率为66.2%。从340份分泌物标本中分离出257株病原菌,其中革兰阴性菌占77.8%,革兰阳性菌占20.6%。汶川地震幸存者分泌物培养中最常见的病原菌为大肠埃希菌(16.3%)、鲍曼不动杆菌(16.0%)、金黄色葡萄球菌(13.6%)、铜绿假单胞菌(12.5%)和阴沟肠杆菌(8.6%)。
医生应高度重视伤口渗出物的药敏试验及抗生素的准确应用,以减少细菌耐药的发生。