Wang Feiyan, Zhang Songtao, Huang Qihong, Shen Yulong, Ni Jinfeng
State Key Lab of Microbial Technology, Shandong University, Jinan 250100, China.
Wei Sheng Wu Xue Bao. 2009 Nov;49(11):1418-23.
Genetic manipulation systems play an important role in the functional analysis of genes and gene products. The development of genetic system in hyperthermophilic archaea is lagging behind those in methanogenic and halophilic archaea. The main problem is the unavailability of efficient selective markers. However, in the past 10 years, researchers have made great progress in the development of genetic systems in the genus Sulfolobus and Thermococcus kodakaraensis, representatives of hyperthermophilic archaea. Here we summarize the latest progress in genetic systems and their application for hyperthermophilic archaea.
遗传操作体系在基因及基因产物的功能分析中发挥着重要作用。嗜热古菌遗传体系的发展落后于产甲烷古菌和嗜盐古菌。主要问题在于缺乏有效的选择标记。然而，在过去十年里，研究人员在嗜热古菌的代表属硫化叶菌属和柯达嗜热栖热菌的遗传体系开发方面取得了重大进展。在此，我们总结了嗜热古菌遗传体系的最新进展及其应用。
Zotero 插件