Department of Stomatognathic Physiology, Malmö University, Malmö, Sweden.
Acta Odontol Scand. 2010 May;68(3):141-7. doi: 10.3109/00016350903514418. Epub 2010 Jan 29.
To study how sense of coherence (SOC), grade of depression and non-specific physical symptoms and general health influence the efficacy of intraoral appliance therapy in patients with temporomandibular disorder (TMD) pain. A second objective was to study the association between SOC, grade of depression, grade of non-specific physical symptoms and general health.
A total of 73 TMD pain patients participated; 36 were treated with a resilient appliance and 37 with a non-occluding control appliance in a randomized controlled trial for a period of 10 weeks. All patients had at least one pain diagnosis according to the research diagnostic criteria for TMD, including both the Symptom Checklist-90-Revised (Axis II) measuring grade of depression and non-specific physical symptoms, and general health (physical characteristics). Patients also filled in the 29-item SOC questionnaire.
A low grade of SOC was found in eight of the patients in the treatment group and in 17 of the control group at baseline, with a statistically significant difference between the groups. Logistic regression analyses revealed that, after correcting for the background variables, the resilient appliance did not differ from the non-occluding control appliance in terms of treatment outcome. No statistically significant differences were found when correlating mean SOC with grade of depression, grade of non-specific physical symptoms and general health.
These findings indicate that none of the studied background variables (age, gender, SOC, depression, non-specific physical symptoms or general health) seemed to influence the short-term efficacy of intraoral appliances. No association was found between SOC and depression, non-specific physical symptoms or general health in TMD pain patients.
研究社会认知（SOC）、抑郁程度、非特异性躯体症状和总体健康状况如何影响口腔内矫治器治疗颞下颌关节紊乱（TMD）疼痛患者的疗效。第二个目的是研究 SOC、抑郁程度、非特异性躯体症状和总体健康之间的相关性。
共有 73 名 TMD 疼痛患者参与了研究；36 名患者接受弹性矫治器治疗，37 名患者接受非阻塞性对照矫治器治疗，为期 10 周。所有患者均根据 TMD 研究诊断标准至少有一个疼痛诊断，包括症状检查表-90-修订版（轴 II）测量抑郁程度和非特异性躯体症状，以及总体健康（身体特征）。患者还填写了 29 项 SOC 问卷。
治疗组中有 8 名患者和对照组中有 17 名患者在基线时 SOC 程度较低，两组间存在统计学差异。逻辑回归分析显示，在校正背景变量后，弹性矫治器与非阻塞性对照矫治器在治疗效果上无差异。当将平均 SOC 与抑郁程度、非特异性躯体症状和总体健康相关联时，未发现统计学差异。
这些发现表明，在所研究的背景变量（年龄、性别、SOC、抑郁、非特异性躯体症状或总体健康）中，没有一个似乎影响口腔内矫治器的短期疗效。在 TMD 疼痛患者中，SOC 与抑郁、非特异性躯体症状或总体健康之间没有关联。
