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肾脏早期评估计划:一种基于社区的筛查方法,旨在解决慢性肾脏病的差异问题。

Kidney early evaluation program: a community-based screening approach to address disparities in chronic kidney disease.

机构信息

National Kidney Foundation and Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.

出版信息

Semin Nephrol. 2010 Jan;30(1):66-73. doi: 10.1016/j.semnephrol.2009.10.004.

Abstract

The Kidney Early Evaluation Program (KEEP) is a free, community-based, kidney disease screening program designed to detect chronic kidney disease (CKD) early and promote follow-up evaluation with clinicians to ultimately improve outcomes. This program screens individuals with diabetes, hypertension, or those with a first-degree relative with diabetes, hypertension, and/or kidney disease. Data based on 89,552 KEEP participants screened in 49 states from early August 2000 until end of December 2007 disclosed a prevalence of 34% African Americans, 12.4% Hispanics, 5.6% Asian/Pacific Islanders, and 4.5% Native Americans. Compared with the random US population sample in National Health and Nutrition Examination Survey 1999 to 2006 and the US Census Bureau 2000, KEEP represented 3-fold more African Americans and Native Americans and a similar proportion of Hispanics and Asians/Pacific Islanders. Analysis of KEEP data confirm that control of CKD risk factors and awareness of CKD remains low. In conclusion, KEEP is an enriched source of populations at high risk for CKD, and control of the two major CKD risk factors, diabetes and hypertension, remains disappointingly low, especially in high-risk populations, despite disease awareness. A longitudinal component of KEEP will evaluate the impact of the program on health disparities over time and holds promise for improving awareness and possibly future management of CKD risk factors.

摘要

肾脏早期评估计划(KEEP)是一个免费的、基于社区的肾脏疾病筛查计划,旨在早期发现慢性肾脏病(CKD),并促进与临床医生的后续评估,最终改善治疗效果。该计划针对患有糖尿病、高血压的个体,或有糖尿病、高血压和/或肾脏疾病的一级亲属的个体进行筛查。2000 年 8 月初至 2007 年 12 月底,49 个州的 89552 名 KEEP 参与者的数据显示,34%的参与者为非裔美国人,12.4%的参与者为西班牙裔,5.6%的参与者为亚洲/太平洋岛民,4.5%的参与者为美国原住民。与 1999 年至 2006 年全国健康和营养调查 1999 年的随机美国人口样本以及 2000 年美国人口普查局相比,KEEP 中的非裔美国人和美国原住民的比例增加了两倍,西班牙裔和亚洲/太平洋岛民的比例相似。KEEP 数据的分析证实,CKD 危险因素的控制和对 CKD 的认识仍然很低。总之,KEEP 是 CKD 高危人群的丰富来源,尽管对疾病有了认识,但控制 CKD 的两个主要危险因素,即糖尿病和高血压,的情况仍令人失望,尤其是在高危人群中。KEEP 的一个纵向部分将评估该计划对随时间推移的健康差异的影响,并有望提高对 CKD 危险因素的认识,并可能改善未来的管理。

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