Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guoxuexiang Street, Chengdu, Sichuan, 610041, China.
J Clin Neurosci. 2010 Apr;17(4):520-2. doi: 10.1016/j.jocn.2009.06.039. Epub 2010 Feb 8.
Giant schwannomas concomitantly involving the intracranial and nasal cavities are rare. We report a 22-year-old male patient with a giant schwannoma involving the frontal skull base and extending into the nasal cavity. The patient had a 2-year history of nasal obstruction that was originally misdiagnosed as nasal polyps. A CT scan and an MRI revealed a large cranionasal tumor. Surgery was performed using a coronal incision with a bilateral frontal skull base extradural approach. The tumor originated from the anterior skull base and the dura and nasal mucosa were intact. Histopathology was consistent with a schwannoma. Schwannoma should be listed as part of the differential diagnosis of a cranionasal tumor and the surgical approach should be carefully selected to achieve total resection.
同时累及颅内和鼻腔的巨大神经鞘瘤较为罕见。我们报告了 1 例 22 岁男性患者，其患有巨大的神经鞘瘤，累及额颅底并延伸至鼻腔。该患者有 2 年的鼻塞病史，最初被误诊为鼻息肉。CT 扫描和 MRI 显示颅面巨大肿瘤。采用冠状切口双侧额骨颅底硬膜外入路进行手术。肿瘤起源于前颅底和硬脑膜，鼻黏膜完整。组织病理学符合神经鞘瘤。神经鞘瘤应列为颅面肿瘤鉴别诊断的一部分，应仔细选择手术入路以实现完全切除。
