[Nutrition and bone health. Protein intake and bone ; pros and cons].

The association of protein intake and bone health is still controversial. The negative effects have been reported such as the association between high protein intake and increasing urinary calcium excretion. In contrast, high protein intake has beneficial effect on bone mineral density (BMD) and bone mineral content (BMC) . Recent meta-analyses or systematic reviews indicate that protein intake dose not promote net loss of whole body calcium, and hence have a small positive effect on BMD and BMC. However, the effect of high protein intake on hip fracture prevention is not supported by previous cohort studies. Therefore, long-term cohort studies are required to clarify the association between protein intake and fracture.