Ng Wan Kee, Ng Yin Kwee, Tan Yung Khan
Australian School of Advanced Medicine, Macquarie University, Sydney, Australia.
J Reprod Med. 2009 Nov-Dec;54(11-12):698-705.
To evaluate the prospective use of the thermography diagnostic system in assessing sexual function in patients with erectile dysfunction (ED).
Thermographs were taken on 14 subjects in a clinical trial conducted at Tan Tock Seng Hospital. After a thorough clinical interview with a standardized questionnaire, patients were scanned for baseline temperature profile before being given an oral dose of sildenafil 100 mg. Subjects were scanned again in the same setting an hour later. If so desired, subjects were given visual stimulation and were allowed minimum direct stimulation, excluding the penis, to elicit erection. Temperature profiles were analyzed using the thermography analysis software in the VarioCAM camera.
Three representative cases are presented to illustrate the potential for using the Infrared thermography (IR) diagnostic system in differentiating psychogenic ED. IR was able to capture a significant difference in blood flow to the corpus cavernosum. Subjects with psychogenic ED have higher surface temperatures (34.3 degrees C +/- 0.71 in the flaccid state and 35.3 degrees C +/- 0.2 during erection) compared to subjects with organic ED (33.64 degrees C +/- 0.4 in flaccid and 33.55 degrees C +/- 0.91 during erection). The difference in surface temperature between flaccid and erected states in subjects with organic ED was not significant.
The proposed diagnostic test based on IR has tremendous clinical potential in differentiating psychogenic ED from organic ED. IR could potentially be a portable, noninvasive and convenient adjunct in the diagnosis and management of ED.
评估热成像诊断系统在评估勃起功能障碍(ED)患者性功能方面的前瞻性应用。
在新加坡陈笃生医院进行的一项临床试验中,对14名受试者进行了热成像检查。在通过标准化问卷进行全面临床访谈后,患者在口服100毫克西地那非之前进行基线体温扫描。一小时后,在相同环境下再次对受试者进行扫描。如果受试者愿意,给予视觉刺激,并允许进行最低限度的直接刺激(不包括阴茎)以诱发勃起。使用VarioCAM相机中的热成像分析软件对温度分布进行分析。
呈现三个代表性案例,以说明使用红外热成像(IR)诊断系统区分心因性ED的潜力。IR能够捕捉到海绵体血流的显著差异。与器质性ED受试者(疲软状态下为33.64℃±0.4,勃起时为33.55℃±0.91)相比,心因性ED受试者的表面温度更高(疲软状态下为34.3℃±0.71,勃起时为35.3℃±0.2)。器质性ED受试者在疲软和勃起状态之间的表面温度差异不显著。
基于IR的拟议诊断测试在区分心因性ED和器质性ED方面具有巨大的临床潜力。IR可能成为ED诊断和管理中一种便携、无创且方便的辅助手段。