Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Early Hum Dev. 2010 Jul;86 Suppl 1:21-5. doi: 10.1016/j.earlhumdev.2010.01.014. Epub 2010 Feb 2.
Extrauterine growth restriction is a common finding among extremely low birth weight infants at discharge from neonatal intensive care units. It has been associated with significant caloric and protein deficits that accumulate during the hospitalization and with slower growth velocity observed with major neonatal morbidities. Recommendations to provide early nutritional support, both parenteral and enteral, have evolved in response to concern about the impact of poor in-hospital growth on growth and neurodevelopmental outcomes in early childhood. This paper will review the evidence supporting the provision of early nutritional support to extremely preterm infants by examining the outcomes associated with such practices.
宫外生长受限是极低出生体重儿从新生儿重症监护病房出院时的常见现象。它与住院期间累积的显著热量和蛋白质不足以及主要新生儿疾病所观察到的生长速度较慢有关。为了关注住院期间生长不良对婴幼儿生长和神经发育结局的影响，人们建议提供早期肠外和肠内营养支持，这一建议随之不断发展。本文将通过检查与这些做法相关的结果，来回顾支持为极早产儿提供早期营养支持的证据。
