Department of International Health, School for Public Health and Primary Care (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.
Eur J Public Health. 2011 Aug;21(4):469-76. doi: 10.1093/eurpub/ckp238. Epub 2010 Jan 31.
The study aims to assess: (i) the association of hostility with socio-demographic, psychosocial and coronary risk factors and (ii) the association of hostility with acute coronary syndrome (ACS) in post-communist secular though predominantly Muslim Albania.
In a population-based case-control study conducted in Tirana in 2003-06, 464 non-fatal sequential ACS patients (368 men, 96 women, 87% response) and a population-sampled control group (n = 684; 449 men, 235 women, 65.5% response) provided data on Cynical Distrust, a measure of hostility. The correlates of hostility in the population sample were assessed using the general linear model and the association of hostility with ACS in the case-control comparison by multivariable-adjusted logistic regression.
In the population-based sample, hostility was related to age (inversely in men), social position, social mobility, relative income (all inverse in both sexes) and emigration of close family. In the case-control comparison, there was a strong graded relationship of hostility with ACS, independent of socio-demographic characteristics and conventional coronary risk factors, including lifestyle/behavioural factors [odds ratio (OR) = 1.25, 95% confidence interval (CI) = 1.18-1.34 in men, and OR = 1.17, 95% CI = 1.05-1.32 in women per unit score of hostility and OR = 5.3, 95% CI = 3.3-8.6 in men and OR = 3.1, 95% CI = 1.1-8.6 in women for upper versus lower tertiles].
This may be the first report from post-communist countries of Eastern and Southeastern Europe or from a Muslim population on the hostility trait in a population-representative sample. Hostility was independently associated with ACS. This requires confirmation, in particular, to exclude the possibility of reverse causality. Hostility may represent an informative risk factor in transitional populations.
本研究旨在评估：（i）敌意与社会人口学、心理社会和冠状动脉危险因素的关系，以及（ii）在后共产主义世俗但主要是穆斯林的阿尔巴尼亚，敌意与急性冠状动脉综合征（ACS）的关系。
在 2003-06 年在地拉那进行的一项基于人群的病例对照研究中，464 例非致命性连续 ACS 患者（368 名男性，96 名女性，87%的应答率）和一个人群抽样对照组（n=684；449 名男性，235 名女性，65.5%的应答率）提供了关于愤世嫉俗的不信任的资料，这是一种敌意的衡量标准。使用一般线性模型评估人群样本中敌意的相关性，并通过多变量调整的逻辑回归评估敌意与病例对照比较中的 ACS 的关系。
在基于人群的样本中，敌意与年龄（男性呈负相关）、社会地位、社会流动性、相对收入（两性均呈负相关）和近亲移民有关。在病例对照比较中，敌意与 ACS 之间存在强烈的分级关系，独立于社会人口学特征和传统的冠状动脉危险因素，包括生活方式/行为因素[比值比（OR）=1.25，95%置信区间（CI）=1.18-1.34，男性；OR=1.17，95%CI=1.05-1.32，女性，每单位敌意评分；OR=5.3，95%CI=3.3-8.6，男性；OR=3.1，95%CI=1.1-8.6，女性，上三分位与下三分位相比]。
这可能是首次来自东欧和东南欧后共产主义国家或穆斯林人群的报告，涉及代表性人群样本中的敌意特征。敌意与 ACS 独立相关。这需要进一步证实，特别是要排除反向因果关系的可能性。在转型人群中，敌意可能是一个有信息价值的危险因素。
