Sun Yong, Yuan Jie, Zhang Ruo-Xi, Yu Bo
Department of Cardiovascular Diseases, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Nov;37(11):1002-5.
To evaluate the therapeutic effect of transcather closure in patients with postinfarction ventricular septal defects (VSD).
Transcatheter VSD closure was performed in 12 patients with postinfarction VSD (10 muscular and 2 membranes defects) on top of standard pharmacotherapy and percutaneous transluminal coronary angioplasty (PTCA) as indicated.
(1) Percutaneous interventional VSD closure was successful in 9 out 12 patients (75%) and these 9 patients survived post procedure. (2) The medial time between VSD occurrence and closure was (15.5 +/- 9.2) days. Procedure-related complications such as device embolization and malignant arrhythmia occurred in 3 patients (25%). The medial time between procedure and discharge from hospital was (11.3 +/- 5.2) days. (3) Coronary angiography was performed in 2 patients and 4 stents were implanted in diseased lesions.
Transcatheter closure could be successfully performed in selected patients with postinfarction VSD.
评估经导管封堵术治疗心肌梗死后室间隔缺损（VSD）患者的疗效。
对12例心肌梗死后VSD患者（10例肌部缺损和2例膜部缺损）在标准药物治疗及必要的经皮腔内冠状动脉成形术（PTCA）基础上进行经导管VSD封堵术。
（1）12例患者中9例（75%）经皮介入VSD封堵成功，这9例患者术后存活。（2）VSD发生至封堵的中位时间为（15.5±9.2）天。3例患者（25%）出现与手术相关的并发症，如封堵器栓塞和恶性心律失常。手术至出院的中位时间为（11.3±5.2）天。（3）2例患者行冠状动脉造影，病变处植入4枚支架。
经导管封堵术可成功应用于部分心肌梗死后VSD患者。
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