单髁膝关节置换术与胫骨高位截骨术治疗单髁膝关节骨关节炎的Meta分析

[Meta-analysis of unicompartmental knee arthroplasty versus high tibial osteotomy in the treatment of unicompartmental knee osteoarthritis].

作者信息

Zhang Qi-Dong, Guo Wan-Shou, Liu Zhao-Hui, Zhang Qian, Cheng Li-Ming, Li Zi-Rong

机构信息

Department of Orthopedics, China-Japan Friendship Hospital, Peking University, Beijing 100029, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2009 Oct 27;89(39):2768-72.

PMID:20137600

Abstract

OBJECTIVE

To assess the efficacy of UKA versus HTO in the treatment of unicompartmental knee osteoarthritis.

METHODS

Comparative studies of UKA and HTO were retrieved from the domestic and foreign literatures and included for a meta-analysis.

RESULTS

Seven eligible randomized controlled trials included 196 UKAs and 219 HTOs. The result of Meta-analysis indicated that the ratio for an excellent outcome was higher in UKA than HTO. The combined OR was 2.43, 95%CI (1.46, 4.05) (P = 0.0006). The risks of revision and complications were lower in UKA than HTO. The combined OR was 0.47 and 0.24 and 95%CI (0.23, 0.97), (0.10, 0.56).

CONCLUSION

UKA reduces the risk of postoperative revision and complications and provides excellent outcomes.

摘要

目的

评估单髁膝关节置换术（UKA）与胫骨高位截骨术（HTO）治疗单间室膝关节骨关节炎的疗效。

方法

从国内外文献中检索UKA和HTO的比较研究并纳入荟萃分析。

结果

七项符合条件的随机对照试验包括196例UKA和219例HTO。荟萃分析结果表明，UKA的优良结果比例高于HTO。合并比值比为2.43，95%置信区间（1.46，4.05）（P = 0.0006）。UKA的翻修和并发症风险低于HTO。合并比值比分别为0.47和0.24，95%置信区间（0.23，0.97），（0.10，0.56）。